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Endothelial microparticles as markers of endothelial dysfunction
Frontiers in Bioscience, 2004Endothelial microparticles (EMP) are small vesicles released from disturbed endothelial cells (EC). Owing to the central importance of EC injury in thrombotic and inflammatory conditions, assay of EMP as a marker of EC disturbance has come under intensive development by several laboratories.
Lawrence L, Horstman +3 more
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Endothelial Dysfunction and Hypertension
Hypertension, 2014The role of the vascular endothelium for hypertension development is not trivial to define. A quiescent healthy endothelium continuously releases potent vasodilators in response to the flowing blood, which have the potential to lower vascular resistance directly.
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Endothelial Dysfunction in Preeclampsia
Seminars in Reproductive Medicine, 1998Several years ago the hypothesis was advanced that alterations of endothelial function could explain much of the pathophysiology of preeclampsia. Since that time, extensive data have been generated to support the hypothesis. Markers of endothelial activation can be demonstrated in women with overt preeclampsia.
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Endothelial Dysfunction in Uraemia
Blood Purification, 2002Cardiovascular disease is a major cause of morbidity and mortality in chronic renal failure (CRF). The endothelium plays a central role in the control of many aspects of vascular function, and abnormalities may contribute to the generation of atherosclerosis.
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Endothelial dysfunction in atherosclerosis
1994Endothelial regulation of vasomotor tone occurs largely via the release of nitric oxide or a closely related compound. This process is strikingly altered in a variety of disease states, and alterations of vasomotion may be responsible for the development of hypertension, altered tissue perfusion, and an enhanced propensity for vasoconstriction in ...
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[Obesity and endothelial dysfunction].
Giornale italiano di cardiologia (2006), 2006The endothelium plays a crucial role in modulating vascular function and structure. In healthy conditions, nitric oxide produced by endothelial cells exerts not only vasodilating properties, but also several other protective actions toward the vessel wall against the development of atherosclerosis and thrombosis. Traditional cardiovascular risk factors
TADDEI, STEFANO +4 more
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Endothelial dysfunction or dysfunctions?
Atherosclerosis, 2008Concetta Irace +4 more
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ED2: Erectile Dysfunction = Endothelial Dysfunction
Endocrinology and Metabolism Clinics of North America, 2007Erectile dysfunction (ED) is a common condition in men, and increases with age. Cardiovascular disease (CVD) is the leading cause of death in men and also increases in prevalence with advancing years. The common link between the two conditions is endothelial dysfunction that leads to vascular insufficiency of the coronary and penile arteries.
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Aging and endothelial dysfunction.
Clinical hemorheology and microcirculation, 2007Aging is the major risk factor for the development of cardiovascular diseases, the leading cause of morbidity, mortality and disability in western countries. Mounting data suggest that cardiovascular structure and function change with time as result of an "aging process", regarded as an independent process which accompanies aging, interwines and ...
COSENTINO, Francesco, E. Osto
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Endothelial Dysfunction in Obesity
2017Chronic inflammatory state in obesity causes dysregulation of the endocrine and paracrine actions of adipocyte-derived factors, which disrupt vascular homeostasis and contribute to endothelial vasodilator dysfunction and subsequent hypertension. While normal healthy perivascular adipose tissue (PVAT) ensures the dilation of blood vessels, obesity ...
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