Results 271 to 280 of about 643,976 (288)

Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development

Advanced Science, EarlyView.
Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu, Le Xie, Yuan Jin, Sen Chen, Xinyu Shi, Yanjun Zong, Zhengdong Zhao, Wei‐Jia Kong, Yu Sun   +8 more
wiley   +1 more source

Association of Inflammation-Based Ratios with Endothelial Dysfunction Markers and Clinical Parameters in Limited Cutaneous Systemic Sclerosis. [PDF]

J Clin Med
Schweiger L, Meinitzer A, Strohmaier H, Moazedi-Fürst F, Nemecz V, Kurzmann-Gütl K, Brodmann M, Hafner F, Jud P.   +8 more
europepmc   +1 more source

Targeted 2‐Deoxy‐D‐Ribose Delivery by Biomimetic Nanoplatform Activates EGFR for Accelerated Heart Valve Endothelialization

Advanced Science, EarlyView.
This study develops a biomimetic nanoplatform using erythrocyte membrane‐camouflaged, CD144 antibody‐functionalized nanoparticles to deliver 2‐deoxy‐D‐ribose (2dDR). This system promotes heart valve endothelialization by enhancing endothelial cell migration and proliferation via EGFR activation, while improving hemocompatibility.
Xiang Qiu, Gaofeng Li, Wenyi Wan, Jinsheng Li, Ge Yan, Shijie Wang, Xiuqi Hu, Zongqi Han, Yazheng Shan, Ying Zhou, Nianguo Dong, Weihua Qiao   +11 more
wiley   +1 more source

Probiotics and Phytoantioxidants Target Coronary Endothelial Dysfunction in Irregular Sleep- and Obesity-Associated Cardiometabolic Syndrome. [PDF]

Life (Basel)
Tseng CN, Chu Y.
europepmc   +1 more source

Integrative Multi‐Omics Analysis Uncovers Immunological Phenotypes Predictive of Combinatorial Immunotherapy Response in Gastric Cancer

Advanced Science, EarlyView.
Current understanding of gastric cancer immunity remains inadequate, leading to suboptimal immunotherapy outcomes. This study introduces a novel tumor immune microenvironment classification system (Inflamed, Desert, and Excluded), advancing traditional histopathological or molecular subtyping toward a functional immunological framework.
Jianchao Wang, Wenfang Zhang, Jiyang Zhang, Chenhui Zhao, Wei Zhang, Menghan Fang, Fangfang Chen, Zhida Wu, Xiaoya Xu, Ziqing Yu, Qiong Zhu, Yi Shi, Dadong Zhang, Xiaofeng Chen, Gang Chen   +14 more
wiley   +1 more source

Immune dysregulation and endothelial dysfunction associate with a pro-thrombotic profile in Long COVID. [PDF]

Front Immunol
Simón-Rueda A, Sánchez-Menéndez C, Casado G, Fuertes D, Murciano-Antón MA, Mateos E, Domínguez-Mateos S, Pozo F, García-Pérez J, Pérez-Olmeda M, Cervero M, Massanella M, Moncunill G, Torres M, Coiras M.   +14 more
europepmc   +1 more source

Corrigendum to “The multi-protective effect of IL-37-Smad3 against ox-LDL induced dysfunction of endothelial cells” [Biomed. Pharmacother. 172 (2024) 116268]

Changyi Zhang, Xiao‐Jun Huang, Bin Xie, Danchun Lian, Jinhao Chen, Weiwen Li, Ying Lin, Xiangna Cai, Jilin Li   +8 more
openalex   +1 more source

Real‐Time In Vivo Monitoring of Anastomotic Intestinal Ischemia Using Implantable Resorbable Organic Sensors

Advanced Science, EarlyView.
Resorbable impedance sensors are successfully implanted into porcine small intestinal anastomoses. Impedance was recorded for 2 hours prior, and 2 hours following ischemia induction, and a significant drop in tissue impedance was observed. Abstract Anastomotic failure remains one of the most severe complications in gastrointestinal surgery.
Dennis Wahl, Finn Jaekel, Julia Henne, Richard Kantelberg, Daniel C. Freund, Eberhard Grambow, Brigitte Vollmar, Amelie R. Zitzmann, Hans Kleemann, Jochen Hampe, Sebastian Hinz, Clemens Schafmayer, Karl Leo   +12 more
wiley   +1 more source

Endothelial Dysfunction in Adolescent Hypertension: Diagnostic Challenges and Early Cardiovascular Risk. [PDF]

J Cardiovasc Dev Dis
Micieta V, Cehakova M, Tonhajzerova I.
europepmc   +1 more source