Results 41 to 50 of about 643,976 (288)

The association between endothelial dysfunction and subclinical myocardial injury in male obstructive sleep apnoea patients

ERJ Open Research
Background Endothelial dysfunction was shown to contribute significantly to the elevated cardiovascular risk observed in the general population. However, the relationship between endothelial dysfunction and subclinical myocardial injury in obstructive ...
Wenhao Cao, Jinmei Luo, Xinjie Hui, Yi Xiao, Rong Huang   +4 more
doaj   +1 more source

The cardiovascular phenotype of adult patients with phenylketonuria [PDF]

, 2019
BACKGROUND: Patients with Phenylketonuria (PKU) are exposed to multiple cardiovascular risk factors, but the clinical significance of these abnormalities is yet unknown.
Azabdaftari, Aline, Giet, Markus van der, Hennermann, Julia B., Plöckinger, Ursula, Querfeld, Uwe, Schuchardt, Mirjam   +5 more
core   +1 more source

Suppression of GRK2 expression reduces endothelial dysfunction by restoring glucose homeostasis

Scientific Reports, 2017
Despite the associations between diabetic complications and vascular endothelial dysfunction, a direct therapeutic method targeting endothelial dysfunction remains poorly characterized.
Kumiko Taguchi, Mari Hida, Mami Hasegawa, Haruka Narimatsu, Takayuki Matsumoto, Tsuneo Kobayashi   +5 more
doaj   +1 more source

Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms [PDF]

, 2018
Hypertension and type 2 diabetes are common comorbidities. Hypertension is twice as frequent in patients with diabetes compared with those who do not have diabetes.
Guzik, Tomasz J., Petrie, John R., Touyz, Rhian M.   +2 more
core   +1 more source

Endothelial Dysfunction, Erectile Dysfunction and Phosphodiesterase 5 Inhibitors. An Update of the Current Data and Future Perspectives

Drug Target Insights, 2007
Endothelial dysfunction is a pathological entity that multiply affects the health status. Erectile dysfunction is being recognized as a condition that is strongly interrelated with endothelial dysfunction, being a vascular event itself.
Angelis Konstantinopoulos, Konstantinos Giannitsas, Spiros Raptis, Petros Perimenis   +3 more
doaj   +2 more sources

Roles of Oxidative Stress and Inflammation in Vascular Endothelial Dysfunction-Related Disease

Antioxidants, 2022
Oxidative stress and chronic inflammation play an important role in the pathogenesis of atherosclerosis. Atherosclerosis develops as the first step of vascular endothelial dysfunction induced by complex molecular mechanisms.
Yukihito Higashi
doaj   +1 more source

Pharmacological activation of endogenous protective pathways against oxidative stress under conditions of sepsis [PDF]

, 2016
Funding The study was funded entirely by institutional funds.Peer ...
Galley, H. F., Lowes, D. A., McCreath, G., Scullion, M. M. F., Webster, N. R.   +4 more
core   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Endothelial Dysfunction in Breast Cancer In-Vivo Model

Proceedings, 2018
Although the endothelial dysfunction is related with tumor development, there is no consensus on the suppressive or supportive effect on tumor growth. The goal of the present study was to evaluate endothelial dysfunction related factors in animal breast ...
Buğra Elkar, Mustafa Barış, Meryem Çalışır, Yasemin Çakır, Safiye Aktaş, Merve Tütüncü, M. Kürşat Şimşek, Mustafa Seçil, Osman Yılmaz, Zekiye Altun   +9 more
doaj   +1 more source

Endothelial Dysfunction and SARS-CoV-2 Infection: Association and Therapeutic Strategies

Pathogens, 2021
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), has been recently considered a systemic disorder leading to the procoagulant state.
Hai Deng, Ting-Xuan Tang, Deng Chen, Liang-Sheng Tang, Xiang-Ping Yang, Zhao-Hui Tang   +5 more
doaj   +1 more source