Results 201 to 210 of about 674,321 (218)

Vascular Endothelial Growth Factor

2003
The striking structural and anatomical parallels between the vasculature and the nervous system is reflected by the fact that these two organ systems appear to use related mechanisms during their development. Thus, it is not surprising that an increasing number of vascular biologists and researchers in the neuroscience field are fascinated by molecules
openaire   +3 more sources

Platelet-derived endothelial cell growth factor

Progress in Growth Factor Research, 1991
AbstractPlatelet‐derived endothelial cell growth factor (PD‐ECGF) is a 45kDa single chain polypeptide which stimulates endothelial cell growth and chemotaxis in vitro and angiogenesis in vivo. Analysis of a full length PD‐ECGF cDNA revealed an open reading frame coding for 482 amino acids without homology to other known proteins. No signal sequence was
Carl-Henrik Heldin, Kohei Miyazono, Kensuke Usuki   +2 more
openaire   +3 more sources

Effect of vascular endothelial growth factor and epidermal growth factor on iatrogenic apoptosis in human endothelial cells

Biochemical Pharmacology, 2004
To study the effect of growth factors on iatrogenic apoptosis, we examined the influence of vascular endothelial growth factor (VEGF) and epidermal growth factor (EGF) on staurosporine-induced apoptosis in primary cultures of human umbilical vein endothelial cells (HUVEC).
VINCI MC, VISENTIN B, CUSINATO F, NARDELLI, GIOVANNI BATTISTA, TREVISI, LUCIA, LUCIANI S.   +5 more
openaire   +3 more sources

Growth factors and endothelial dysfunction.

Drugs, 1999
Endothelial dysfunction has been implicated in the pathogenesis of many cardiovascular diseases; experimental and clinical studies have shown that endothelial dysfunction may be a key factor in various processes, including abnormal arterial vasomotion, thrombosis or neointimal proliferation. Endothelial dysfunction has been shown to be a characteristic
C, Bauters, I, Six, T, Meurice, E, Van Belle   +3 more
openaire   +2 more sources

Vascular Endothelial Growth Factor in Cervical Carcinoma

Obstetrics & Gynecology, 1999
To quantitate vascular endothelial growth factor of cervical carcinoma and elucidate its clinical correlation.Intratumoral protein levels of vascular endothelial growth factor were measured in 104 cervical cancer patients and in 30 cervical tissue specimens of benign gynecologic diseases as controls. The concentrations were correlated with clinical and
Fon-Jou Hsieh, Chang-Yao Hsieh, Chien-Nan Lee, Tzer-Ming Chen, Wen-Fang Cheng, Chi-An Chen   +5 more
openaire   +3 more sources

Role of Vascular Endothelial Growth Factor and Vascular Endothelial Growth Factor Receptors in Vascular Development

1999
Distinct cellular processes mediate blood-vessel formation during embryogenesis (Beck and D’Amore 1997; Carmeliet and Collen 1998a; Folkman and D’Amore 1996; Noden 1989; Risau 1997; Wilting and Christ 1996) (Fig. 1). Initially, mesodermal cells differentiate in situ into early haemangioblasts and form cellular aggregates (blood islands), in which the ...
Peter Carmeliet, Desire Collen
openaire   +3 more sources

Hypertension and Vascular Endothelial Growth Factors

2015
The members of vascular endothelial growth factors (VEGF) are the principal regulators of angiogenesis and vascular biology. The specific growth factor of the endothelial cells is VEGF, which produces nitric oxide (NO) from endothelial cells causing vasodilation.
Luizon, Marcelo Rizzatti, Sandrim, Valeria Cristina   +1 more
openaire   +3 more sources

Vascular Endothelial Growth Factor and its Receptors

Retina, 1994
Vascular endothelial growth factor (VEGF) is a highly specific mitogen for vascular endothelial cells and an angiogenic factor that is structurally related to platelet derived growth factor (PDGF). It is also known as the vascular permeability factor (VPF) because it efficiently potentiates the permeabilization of blood vessels. Five types of VEGF mRNA
Gera Neufeld, Ben-Zion Levi, Hela Gitay-Goren, Shoshana Tessler, Tzafra Cohen   +4 more
openaire   +3 more sources

Effects of Finasteride on Vascular Endothelial Growth Factor

Scandinavian Journal of Urology and Nephrology, 2002
Finasteride has been shown to reduce prostate bleeding in patients with benign prostatic hyperplasia (BPH). The mechanisms behind this are not known, but it has been suggested that finasteride reduces bleeding by inhibiting angiogenesis in the prostate. Studies in animals have shown that castration rapidly induces involution of the prostate vasculature,
Häggström, S., Tørring, Niels, Møller, K., Jensen, E., Lund, L., Nielsen, J.E., Bergh, A., Damber, J.-E.   +7 more
openaire   +4 more sources

Endothelial Growth Factor Receptors in Angiogenesis

2013
It is hard to underestimate the role of endothelial growth factor receptors in the generation of new blood vessels. This axis is involved in vascular development in embryos and angiogenesis in adults. As the signaling of these tyrosine kinase receptors has been elucidated, we have gained an appreciation of the complex interactions with other receptors,
Peng H. Tan, David Bruce
openaire   +2 more sources