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Endothelial progenitor cell-conditioned medium promotes angiogenesis and is neuroprotective after spinal cord injury

open access: yesNeural Regeneration Research, 2018
Endothelial progenitor cells secrete a variety of growth factors that inhibit inflammation, promote angiogenesis and exert neuroprotective effects. Therefore, in this study, we investigated whether endothelial progenitor cell-conditioned medium might ...
Tao Wang, Xiao Fang, Zong-Sheng Yin
doaj   +2 more sources

Endothelial Progenitor Cell [PDF]

open access: yesDefinitions, 2020
Yo Iwami, H. Masuda, T. Asahara
semanticscholar   +2 more sources

Endothelial Progenitor Cells [PDF]

open access: yesNew England Journal of Medicine, 2003
Vascular endothelial cells form a lining — one cell thick — for all the blood vessels in the body, providing a critical interface between the vessel itself and blood-borne elements.
Takayuki Asahara, Jeffrey M. Isner
  +6 more sources

Circulating endothelial progenitor cells [PDF]

open access: yesBritish Journal of Cancer, 2005
Angiogenesis research investigates the formation of new blood vessels in wound healing, tumour growth and embryonic development. Circulating, bone marrow-derived endothelial progenitor cells (EPCs) were first described 8 years ago, yet the exact nature of these endothelial precursor cells remains unclear.
Garmy-Susini, B, Varner, J A
  +6 more sources

Endothelial Progenitor Cells [PDF]

open access: yesAnnual Review of Medicine, 2005
Endothelial progenitor cells are a circulating, bone marrow–derived cell population that appears to participate in both vasculogenesis and vascular homeostasis. Questions persist regarding their functional characteristics, as well as the precise panel of cell surface markers that uniquely define this newly described progenitor cell population.
Aarif Y, Khakoo, Toren, Finkel
openaire   +4 more sources

CXCL13/CXCR5 axis facilitates endothelial progenitor cell homing and angiogenesis during rheumatoid arthritis progression

open access: yesCell Death and Disease, 2021
Angiogenesis is a critical process in the formation of new capillaries and a key participant in rheumatoid arthritis (RA) pathogenesis. The chemokine (C-X-C motif) ligand 13 (CXCL13) plays important roles in several cellular functions such as ...
Chun-Hao Tsai   +8 more
semanticscholar   +1 more source

Effect of endothelial progenitor cell-derived extracellular vesicles on endothelial cell ferroptosis and atherosclerotic vascular endothelial injury

open access: yesCell Death Discovery, 2021
Atherosclerosis (AS) is a chronic inflammatory disorder characterized by endothelial dysfunction. Endothelial progenitor cells (EPCs) can overcome endothelial dysfunction and reduce AS risk.
Lin Li   +5 more
semanticscholar   +1 more source

Mobilizing Endothelial Progenitor Cells [PDF]

open access: yesHypertension, 2005
Mobilization of endogenous endothelial progenitor cells (EPCs) from the bone marrow may be an alternative way to increase neovascularization and may be used as therapeutic option for the treatment of ischemic cardiovascular diseases. In this review, we discuss the EPC mobilizing effects of pro-inflammatory cytokines such as granolocyte monocyte colony ...
Alexandra, Aicher   +2 more
openaire   +2 more sources

Placental growth factor expression is required for bone marrow endothelial cell support of primitive murine hematopoietic cells. [PDF]

open access: yesPLoS ONE, 2013
Two distinct microenvironmental niches that regulate hematopoietic stem/progenitor cell physiology in the adult bone marrow have been proposed; the endosteal and the vascular niche.
Xiaoying Zhou   +2 more
doaj   +1 more source

Induction of Neurogenesis and Angiogenesis in a Rat Hemisection Spinal Cord Injury Model With Combined Neural Stem Cell, Endothelial Progenitor Cell, and Biomimetic Hydrogel Matrix Therapy

open access: yesCritical Care Explorations, 2021
OBJECTIVES:. Acute spinal cord injury is a devastating injury that may lead to loss of independent function. Stem-cell therapies have shown promise; however, a clinically efficacious stem-cell therapy has yet to be developed.
Eric J. Marrotte, DO, PhD   +6 more
doaj   +1 more source

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