Results 21 to 30 of about 634,512 (305)

Endothelial progenitor cells in chronic obstructive pulmonary disease and emphysema.

PLoS ONE, 2017
Endothelial injury is implicated in the pathogenesis of COPD and emphysema; however the role of endothelial progenitor cells (EPCs), a marker of endothelial cell repair, and circulating endothelial cells (CECs), a marker of endothelial cell injury, in ...
Margaret F Doyle, Russell P Tracy, Megha A Parikh, Eric A Hoffman, Daichi Shimbo, John H M Austin, Benjamin M Smith, Katja Hueper, Jens Vogel-Claussen, Joao Lima, Antoinette Gomes, Karol Watson, Steven Kawut, R Graham Barr   +13 more
doaj   +1 more source

Single-Cell Transcriptional Profiling of Aortic Endothelium Identifies a Hierarchy from Endovascular Progenitors to Differentiated Cells

Cell Reports, 2019
Summary: The cellular and molecular profiles that govern the endothelial heterogeneity of the circulatory system have yet to be elucidated. Using a data-driven approach to study the endothelial compartment via single-cell RNA sequencing, we characterized
Samuel W. Lukowski, Jatin Patel, Stacey B. Andersen, Seen-Ling Sim, Ho Yi Wong, Joshua Tay, Ingrid Winkler, Joseph E. Powell, Kiarash Khosrotehrani   +8 more
doaj   +1 more source

Single-cell RNA sequencing based analysis depicts the development map of human early embryonic erythrocytes [PDF]

Jichu yixue yu linchuang, 2022
Objective Single-cell RNA sequencing (scRNA-seq) was used to systematically delineate the cell atlas and molecular tracks of human early erythroid development at the single-cell level.
CHEN Zhong-yang, MA Yan-ni, YU Jia
doaj   +1 more source

Glucocerebroside reduces endothelial progenitor cell-induced angiogenesis

Food and Agricultural Immunology, 2019
The recruitment of bone marrow-derived endothelial progenitor cells (EPCs) facilitates physiological and pathological processes involved in new blood vessel synthesis.
Hsiang-Ping Lee, Shih-Wei Wang, Yang-Chang Wu, Chang-Hai Tsai, F. Tsai, Jing-Gung Chung, Chih-Yang Huang, Jai-Sing Yang, Y. Hsu, M. Yin, Te-Mao Li, Chih-Hsin Tang   +11 more
semanticscholar   +1 more source

Protective Effects of Endothelial Progenitor Cell‐Derived Extracellular Mitochondria in Brain Endothelium

Stem Cells, 2018
Endothelial progenitor cells (EPCs) have been pursued as a potential cellular therapy for stroke and central nervous system injury. However, their underlying mechanisms remain to be fully defined. Recent experimental studies suggest that mitochondria may
K. Hayakawa, S. Chan, E. Mandeville, J. H. Park, Morgan Bruzzese, J. Montaner, K. Arai, A. Rosell, E. Lo   +8 more
semanticscholar   +1 more source

Endothelial stem and progenitor cells (stem cells): (2017 Grover Conference Series)

Pulmonary Circulation, 2017
The capacity of existing blood vessels to give rise to new blood vessels via endothelial cell sprouting is called angiogenesis and is a well-studied biologic process.
Mervin C. Yoder
doaj   +1 more source

Transcriptomic Remodelling of Fetal Endothelial Cells During Establishment of Inflammatory Memory

Frontiers in Immunology, 2021
Inflammatory memory involves the molecular and cellular ‘reprogramming’ of innate immune cells following exogenous stimuli, leading to non-specific protection against subsequent pathogen exposure.
Elisa Weiss, Amanda Vlahos, Bowon Kim, Sachintha Wijegunasekara, Dhanya Shanmuganathan, Thomas Aitken, Thomas Aitken, Ji-Hoon E. Joo, Ji-Hoon E. Joo, Samira Imran, Samira Imran, Rebecca Shepherd, Jeffrey M. Craig, Jeffrey M. Craig, Jeffrey M. Craig, Mark Green, Ursula Hiden, Boris Novakovic, Boris Novakovic, Richard Saffery, Richard Saffery   +20 more
doaj   +1 more source

Endothelial progenitor cell transplantation alleviated ischemic brain injury via inhibiting C3/C3aR pathway in mice

Journal of Cerebral Blood Flow and Metabolism, 2019
Endothelial progenitor cell transplantation is a potential therapeutic approach in brain ischemia. However, whether the therapeutic effect of endothelial progenitor cells is via affecting complement activation is unknown.
Yuanyuan Ma, Lu Jiang, Liping Wang, Yongfang Li, Yanqun Liu, Wenjing Lu, Rubing Shi, Linyuan Zhang, Zongjie Fu, M. Qu, Yingling Liu, Yongting Wang, Zhi-jun Zhang, Guo-Yuan Yang   +13 more
semanticscholar   +1 more source

VEGF promotes endothelial progenitor cell differentiation and vascular repair through connexin 43

Stem cell research & therapeutics, 2017
Endothelial progenitor cell (EPC) differentiation is considered crucial for vascular repair. Vascular endothelial growth factor (VEGF) induces EPC differentiation, but the underlying mechanism of this phenomenon remains unclear.
Lufeng Li, Huanyun Liu, Chunxin Xu, Meng-yang Deng, Ming-bao Song, Xuejun Yu, Shangcheng Xu, Xiaohui Zhao   +7 more
semanticscholar   +1 more source

Endothelial Progenitor Cells in Prehypertension

Current Pharmaceutical Design, 2011
Blood pressure within prehypertensive levels confers higher cardiovascular risk. As prehypertension is also an intermediate stage for full hypertension, a precocious intervention with lifestyle changes or drugs is therefore appealing. Endothelial injury and dysfunction are thought to contribute to cardiovascular risk in prehypertension.
DI STEFANO, ROSSELLA, Barsotti MC, FELICE, FRANCESCA, Vlachopoulos C, BALBARINI, ALBERTO   +4 more
openaire   +4 more sources