Results 51 to 60 of about 634,512 (305)

Nestin Protein Is Phosphorylated in Adult Neural Stem/Progenitor Cells and Not Endothelial Progenitor Cells

Stem Cells International, 2012
An intermediate filament protein, Nestin, is known as a neural stem/progenitor cell marker. It was shown to be required for the survival and self-renewal of neural stem cells according to the phenotypes of Nestin knockout mice. Nestin expression has also
Jun Namiki, Sayuri Suzuki, Takeshi Masuda, Yasushi Ishihama, Hideyuki Okano   +4 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Fractalkine expression induces endothelial progenitor cell lysis by natural killer cells. [PDF]

PLoS ONE, 2011
BACKGROUND: Circulating CD34(+) cells, a population that includes endothelial progenitors, participate in the maintenance of endothelial integrity.
Dilyana Todorova, Florence Sabatier, Evelyne Doria, Luc Lyonnet, Henri Vacher Coponat, Stéphane Robert, Nicolas Despoix, Tristan Legris, Valérie Moal, Anderson Loundou, Sophie Morange, Yvon Berland, Francoise Dignat George, Stéphane Burtey, Pascale Paul   +14 more
doaj   +1 more source

Endothelial Progenitor Cells in Cerebrovascular Disease [PDF]

Stroke, 2005
To the Editor: In their interesting article, Ghani and colleagues reported a reduction in endothelial progenitor cells (EPCs) in patients with cerebrovascular disease, when compared with healthy control subjects.1 However, the authors did not mention a recent article by Taguchi et al reporting that CD34+ cells and CD133+ cells, as an EPC-enriched ...
FADINI, GIAN PAOLO, AGOSTINI, CARLO, AVOGARO, ANGELO   +2 more
openaire   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Bone Marrow Alterations and Lower Endothelial Progenitor Cell Numbers in Critical Limb Ischemia Patients

PLoS ONE, 2013
Background Critical limb ischemia (CLI) is characterized by lower extremity artery obstruction and a largely unexplained impaired ischemic neovascularization response.
M. Teraa, R. Sprengers, P. E. Westerweel, H. Gremmels, M. Goumans, T. Teerlink, F. Moll, M. Verhaar   +7 more
semanticscholar   +1 more source

Prehypertension and endothelial progenitor cell function [PDF]

Journal of Human Hypertension, 2010
Prehypertension is associated with significant damage to the coronary vasculature and increased rates of adverse cardiovascular events. Circulating endothelial progenitor cells (EPCs) are critical to vascular repair and the formation of new blood vessels. We tested the hypothesis that prehypertension is associated with EPC dysfunction. Peripheral blood
MacEneaney, OJ, DeSouza, C A, Weil, B R, Kushner, E J, Van Guilder, Gary, Mestek, M L, Greiner, J J, Stauffer, B L   +7 more
openaire   +2 more sources

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Effects of Endothelial Progenitor Cell-Derived Microvesicles on Hypoxia/Reoxygenation-Induced Endothelial Dysfunction and Apoptosis

Oxidative Medicine and Cellular Longevity, 2013
Oxidative stress-induced endothelial dysfunction plays a key role in ischemia/reperfusion injury. Recent evidence indicates that endothelial progenitor cell-derived microvesicles (EPC-MVs) can promote angiogenesis of endothelial cells (ECs).
Jinju Wang, Shuzhen Chen, Xiaotang Ma, Chuan-fang Cheng, Xiang-wen Xiao, Ji Chen, Shiming Liu, Bin Zhao, Yanfang Chen   +8 more
semanticscholar   +1 more source

Endothelial Progenitor Cells in Diabetic Retinopathy [PDF]

Frontiers in Endocrinology, 2014
Diabetic retinopathy (DR) is a leading cause of visual impairment worldwide. Patients with DR may irreversibly lose sight as a result of the development of diabetic macular edema (DME) and/or proliferative diabetic retinopathy (PDR); retinal blood vessel dysfunction and degeneration plays an essential role in their pathogenesis. Although new treatments
Lois, Noemi, McCarter, Rachel V, O'Neill, Christina, Medina, Reinhold J, Stitt, Alan W   +4 more
openaire   +5 more sources