Results 261 to 270 of about 746,723 (389)

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

open access: yesAdvanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue   +17 more
wiley   +1 more source

The Impact of Modern Anti-Diabetic Treatment on Endothelial Progenitor Cells. [PDF]

open access: yesBiomedicines, 2023
Altabas V   +4 more
europepmc   +1 more source

Exercise Induces Stromal Cell–Derived Factor-1&agr;–Mediated Release of Endothelial Progenitor Cells with Increased Vasculogenic Function

open access: yesPlastic and Reconstructive Surgery, 2015
E. Chang   +12 more
semanticscholar   +1 more source

Micro‐Organ Chip Deciphers Tumor‐Derived G‐CSF as Remote Commander of Lung Pre‐Metastatic Niche via VEGFA‐KDR Cascade

open access: yesAdvanced Science, EarlyView.
Breast cancer reprograms the lung into a receptive pre‐metastatic niche via a novel G‐CSF–VEGFA–KDR signaling axis. Using a micro‐organ chip that enables contact‐independent coculture, this study uncovers how tumor‐secreted G‐CSF activates lung capillary KDR to drive angiogenesis and prime the soil for metastasis—without direct tumor contact.
Jingxin Zhang   +12 more
wiley   +1 more source

Endothelial progenitor cells as biomarkers of diabetes-related cardiovascular complications. [PDF]

open access: yesStem Cell Res Ther, 2023
Benítez-Camacho J   +7 more
europepmc   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

open access: yesAdvanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang   +2 more
wiley   +1 more source

Endothelial progenitor cells as an angiogenic biomarker for the diagnosis and prognosis of lung cancer. [PDF]

open access: yesRep Pract Oncol Radiother
Najjar F   +7 more
europepmc   +1 more source

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