Results 291 to 300 of about 268,157 (315)

Angiogenesis as a Therapeutic Target of (Poly)phenols: Tackling Cancer and Vascular‐Related Complications

Molecular Nutrition &Food Research, EarlyView.
(Poly)phenols constitute a source of natural therapeutic molecules capable of targeting angiogenesis in different scenarios. This review summarizes the current evidence of the role of (poly)phenols in modulating angiogenesis. The reader can find a compilation of preclinical and human investigations describing pro‐ and anti‐angiogenic effects of these ...
María Ángeles Ávila‐Gálvez, Antonio Vico‐Padilla, Claus Schneider, Juan Carlos Espín, Antonio González‐Sarrías, Juan Antonio Giménez‐Bastida   +5 more
wiley   +1 more source

Clinical usefulness of endothelial progenitor cells in predicting the efficacy of riociguat in chronic thromboembolic pulmonary hypertension. [PDF]

Nagoya J Med Sci
Imai R, Adachi S, Yoshida M, Shimokata S, Nakano Y, Okumura N, Murohara T, Kondo T.   +7 more
europepmc   +1 more source

The role of miR‐4284 in cancer progression and therapeutic response: Regulatory mechanisms and clinical implications

Malignancy Spectrum, EarlyView.
As a pivotal microRNA (miRNA), miR‐4284 exhibits noteworthy aberrant expression levels across various cancers and diseases, exerting a crucial role in modulating cancer progression and prognosis. Additionally, the article reviews the potential correlations between miR‐4284 and various contemporary treatment modalities, including but not limited to the ...
Chenhao Liang, Yaojie Feng, Yuhua Zhang, Zehua Wang, Xinming Su, Shiwei Duan   +5 more
wiley   +1 more source

Linc-ROR Modulates the Endothelial-Mesenchymal Transition of Endothelial Progenitor Cells through the miR-145/Smad3 Signaling Pathway. [PDF]

Physiol Res
Liang J, Chu H, Ran Y, Lin R, Cai Y, Guan X, Cui X, Zhang X, Li H, Cheng M.   +9 more
europepmc   +1 more source

Role of astrocyte in neuroinflammation‐induced loss in neuroplasticity and subsequent onset of depression: A systematic review

Neuroprotection, EarlyView.
Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal, Saurabh Singhal, Bernhard T. Baune   +2 more
wiley   +1 more source

LncRNA Growth Arrest Specific 5 Promotes Glucose Metabolism Reprogramming Via the IGF2BP1/SIX1 Axis and Inhibits Ferroptosis of Endothelial Progenitor Cells Via the miR-23a-3p/SLC7A11 Axis in Coronary Heart Disease. [PDF]

Anatol J Cardiol
Zhong M, Xu W, Tang B, Zhao Q, Jiang Z, Liu Y.   +5 more
europepmc   +1 more source

Effects of obesity‐associated plasma markers on adipose stem cell function and epigenetic regulation

Obesity, EarlyView.
Abstract Objective This study investigates the correlations between obesity‐related plasma markers and epigenetic/inflammatory changes in white adipose tissue (WAT), focusing on adipose‐derived stem cells (ASCs). We hypothesize that obesity modulates histone H3K27 marks, modified by demethylases (lysine‐specific demethylase 6A and 6B [KDM6A/KDM6B]) and
Andressa França Sousa Bispo, Jussara de Jesus Simao, Miguel Ambrizzi Moraes, Ana Beatriz Marques Abel, Victor Tadeu Gonçalves Plata, Monica Marques Telles, André Valente Santana, Paula Volpe, Lucia Maria Armelin‐Correa, Maria Isabel Cardoso Alonso‐Vale   +9 more
wiley   +1 more source

Combination of melatonin-delivered endothelial progenitor cells with S-nitroso-N-acetyl-DL-penicillamine for improving critical limb ischemia in the rat. [PDF]

Am J Transl Res
Yeh JN, Yip HK, Shao PL, Chiang JY, Wu SC, Sung PH, Sheu JJ, Guo J.   +7 more
europepmc   +1 more source

Post‐COVID‐19 condition: clinical phenotypes, pathophysiological mechanisms, pathology, and management strategies

The Journal of Pathology, EarlyView.
Abstract Post‐COVID‐19 condition (PCC), also known as long COVID, is a complex multiple organ system condition that can develop and persist for months after acute COVID‐19. PCC encompasses a wide range of symptoms, resulting in heterogeneous clinical manifestations. These manifestations likely arise from diverse underlying pathophysiological mechanisms,
Larissa E Vlaming‐van Eijk, Guolu Tang, Arno R Bourgonje, Wilfred F A den Dunnen, Jan‐Luuk Hillebrands, Harry van Goor   +5 more
wiley   +1 more source