Results 91 to 100 of about 1,444,041 (282)

Physical Binding of Endothelial MCAM and Neural Transmembrane Protease Matriptase—Novel Cell Adhesion in Neural Stem cell Vascular Niche

Scientific Reports, 2017
Brain neural stem cells and transit amplifying cells in the subventricular zone (SVZ) of the lateral ventricles are in direct contact with the microvascular endothelium.
Hsiu-Hui Tung, Sheau-Ling Lee
doaj   +1 more source

The Current Use of Stem Cells in Bladder Tissue Regeneration and Bioengineering. [PDF]

, 2017
Many pathological processes including neurogenic bladder and malignancy necessitate bladder reconstruction, which is currently performed using intestinal tissue. The use of intestinal tissue, however, subjects patients to metabolic abnormalities, bladder
Chan, Yvonne Y, Kurzrock, Eric A, Osborn, Stephanie L, Sandlin, Samantha K   +3 more
core   +2 more sources

A vascular endothelial growth factor–loaded chitosan-hyaluronic acid hydrogel scaffold enhances the therapeutic effect of adipose-derived stem cells in the context of stroke

Neural Regeneration Research
Adipose-derived stem cell, one type of mesenchymal stem cells, is a promising approach in treating ischemia-reperfusion injury caused by occlusion of the middle cerebral artery.
Zhijian Zheng, Xiaohui Lin, Zijun Zhao, Qiang Lin, Ji Liu, Manli Chen, Wenwen Wu, Zhiyun Wu, Nan Liu, Hongbin Chen   +9 more
doaj   +1 more source

Endothelial cells maintain neural stem cells quiescent in their niche [PDF]

Neuroscience, 2017
Niches are specialized microenvironments that regulate stem cells' activity. The neural stem cell (NSC) niche defines a zone in which NSCs are retained and produce new cells of the nervous system throughout life. Understanding the signaling mechanisms by which the niche controls the NSC fate is crucial for the success of clinical applications.
Alexander Birbrair, Alexander Birbrair, Pedro H.D.M. Prazeres, Gabryella S P Santos, Patrick O. Azevedo, Luiza Lousado, Isadora F. G. Sena, Ana E. Paiva, Akiva Mintz, Renato Filev, Julia P. Andreotti   +10 more
openaire   +2 more sources

Host-microbe interactions at the blood-brain barrier through the lens of induced pluripotent stem cell-derived brain-like endothelial cells

mBio
Microbe-induced meningoencephalitis/meningitis is a life-threatening infection of the central nervous system (CNS) that occurs when pathogens are able to cross the blood-brain barrier (BBB) and gain access to the CNS.
Nadine Vollmuth, Jon Sin, Brandon J. Kim
doaj   +1 more source

Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival [PDF]

, 2006
There are two types of neural stem cells (NSCs). Primitive NSCs [leukemia inhibitory factor (LIF) dependent but exogenous fibroblast growth factor (FGF) 2 independent] can be derived from mouse embryonic stem (ES) cells in vitro and from embryonic day 5 ...
Chaddah, R, Ema, M, Haigh, Jody, Hitoshi, S, Nagy, A, Rossant, J, van der Kooy, D, Wada, T   +7 more
core   +3 more sources

Functional Characterization of Embryonic Stem Cell-Derived Endothelial Cells [PDF]

Journal of Vascular Research, 2011
Endothelial cells (EC) derived from embryonic stem cells (ESC) require additional functional characterization before they are used as a cell therapy in order to enhance their potential for engraftment and proliferation. We explore several physiologically relevant functions of ESC-derived EC (ESC-EC), such as its capacity to produce nitric oxide (NO ...
Glaser, Drew E., Gower, Robert M., Lauer, Nicholas E., Tam, Kayan, Blancas, Alicia A., Shih, Albert J., Simon, Scott I., McCloskey, Kara E.   +7 more
openaire   +3 more sources

The light and shadow of senescence and inflammation in cardiovascular pathology and regenerative medicine [PDF]

, 2017
Recent epidemiologic studies evidence a dramatic increase of cardiovascular diseases, especially associated with the aging of the world population. During aging, the progressive impairment of the cardiovascular functions results from the compromised ...
Cavarretta, Elena, Dal Sasso, Eleonora, Forte, Maurizio, Frati, Giacomo, Gerosa, Gino, Iop, Laura, Palmerio, Silvia, Peruzzi, Mariangela, Schirone, Leonardo, Sciarretta, Sebastiano   +9 more
core   +4 more sources

Bone Morphogenetic Protein 9 Regulates Early Lymphatic-Specified Endothelial Cell Expansion during Mouse Embryonic Stem Cell Differentiation

Stem Cell Reports, 2019
Summary: Exogenous cues involved in the regulation of the initial steps of lymphatic endothelial development remain largely unknown. We have used an in vitro model based on the co-culture of vascular precursors derived from mouse embryonic stem cell (ESC)
Mariela Subileau, Galina Merdzhanova, Delphine Ciais, Véronique Collin-Faure, Jean-Jacques Feige, Sabine Bailly, Daniel Vittet   +6 more
doaj  

Constructing an Isogenic 3D Human Nephrogenic Progenitor Cell Model Composed of Endothelial, Mesenchymal, and SIX2-Positive Renal Progenitor Cells

Stem Cells International, 2019
Urine has become the source of choice for noninvasive renal epithelial cells and renal stem cells which can be used for generating induced pluripotent stem cells.
Lisa Nguyen, Lucas-Sebastian Spitzhorn, James Adjaye   +2 more
doaj   +1 more source