Results 101 to 110 of about 5,863,268 (295)

Endothelial Differentiation of Embryonic Stem Cells [PDF]

, 2011
Embryonic stem (ES) cells are a rich source of multiple different cell types of diverse lineages. Significant advances have recently been made in our understanding of the molecular mechanisms by which ES cells differentiate into endothelial cells.
openaire   +1 more source

Supporting data on in vitro cardioprotective and proliferative paracrine effects by the human amniotic fluid stem cell secretome

Data in Brief, 2019
The data and information presented here refer to the research article entitled: “Reactivating endogenous mechanisms of cardiac regeneration via paracrine boosting with the human amniotic fluid stem cell secretome” (Balbi et al., 2019, Apr 04).
Carolina Balbi, Kirsten Lodder, Ambra Costa, Silvia Moimas, Francesco Moccia, Tessa van Herwaarden, Vittorio Rosti, Francesca Campagnoli, Agnese Palmeri, Pierangela De Biasio, Francesco Santini, Mauro Giacca, Marie-Josè Goumans, Lucio Barile, Anke M. Smits, Sveva Bollini   +15 more
doaj   +1 more source

Stem Cell-Derived Endothelial Cell Model that Responds to Tobacco Smoke Like Primary Endothelial Cells

Chemical Research in Toxicology, 2020
To clarify how smoking leads to heart attack and stroke, we developed an endothelial cell model (iECs) generated from human induced Pluripotent Stem Cells (iPSC) and evaluated its responses to tobacco smoke. These iECs exhibited a uniform endothelial morphology, and expressed markers PECAM1/CD31, VWF/ von Willebrand Factor, and CDH5/VE-Cadherin.
Pei-Hsuan Chu, Guibin Chen, David Kuo, John Braisted, Ruili Huang, Yuhong Wang, Anton Simeonov, Manfred Boehm, David L. Gerhold   +8 more
openaire   +3 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Heterogeneity of the adult mammalian forebrain neurogenic ependyma: A comprehensive cellular map

Neural Regeneration Research
The presence or absence of adult neural stem cells in the mammalian forebrain ependyma has been debated for two decades. In this study, we performed single-cell RNA sequencing to investigate the cellular composition of the ependymal surface of the adult ...
Xuejiao Yang, Yuchen Mu, Qianxiang Wu, Liqiang Zhou, Orion R. Fan, Quan Lin, Wenmin Zhu, Yi Eve Sun   +7 more
doaj   +1 more source

Determinants of Body Mass Index in Early Systemic Sclerosis: Implications for Nutritional Risk Stratification

Arthritis Care &Research, EarlyView.
Objective Gastrointestinal (GI) involvement can lead to malnutrition in patients with systemic sclerosis (SSc). Body mass index (BMI) remains the most widely used marker to screen nutritional status. We aimed to identify predictors of lower BMI in patients with SSc. Methods Patients with SSc from a prospective US cohort meeting 2013 American College of
Ali Y. Ayla, Meng Zhang, Bingrui Chen, Claudia Pedroza, Brian Skaug, Maureen Mayes, Michael Hughes, Shervin Assassi, Zsuzsanna H. McMahan   +8 more
wiley   +1 more source

Dielectrophoresis: A Review of Applications for Stem Cell Research [PDF]

, 2010
Dielectrophoresis can discriminate distinct cellular identities in heterogeneous populations, and monitor cell state changes associated with activation and clonal expansion, apoptosis, and necrosis, without the need for biochemical labels.
De Sousa, Paul, Ronald Pethig, Pells, Steve, Anoop Menachery, Menachery, Anoop, Paul De Sousa, Pethig, Ronald, Steve Pells   +7 more
core   +1 more source

Advancements in Cellular Therapeutics in Corneal Diseases

Cells
Disorders of the cornea are responsible for a significant portion of preventable blindness worldwide. Various types of corneal transplantation procedures have successfully restored vision in many individuals; however, they carry the risk of graft failure
Elizabeth Woo, Daniel Henick, Maryam Tahvildari   +2 more
doaj   +1 more source

Mobilization of bone marrow-derived progenitor cells in acute coronary syndromes.

Folia Histochemica et Cytobiologica, 2005
Two hypotheses explain the role of adult progenitor cells in myocardial regeneration. Stem cell plasticity which involves mobilization of stem cells from the bone marrow and other niches, homing to the area of tissue injury and transdifferentiation into ...
Wojciech Wojakowski, Michał Tendera
doaj   +1 more source