Results 31 to 40 of about 430,240 (358)
Transdifferentiation of cancer stem cells into endothelial cells [PDF]
Open Life Sciences, 2011 Abstract Vasculogenic mimicry was first described as the unique ability of aggressive melanoma cells to express an endothelial phenotype and to form vessel-like networks in three dimensional cultures, “mimicking” the pattern of embryonic vascular networks and recapitulating the patterned networks seen in patients with aggressive tumors ...
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Cell Reports, 2020 Summary: Development of blood-forming (hemogenic) endothelial cells that give rise to hematopoietic stem and progenitor cells (HSPCs) is critical during embryogenesis to generate the embryonic and postnatal hematopoietic system.
Jingyao Qiu +4 more
doaj +1 more source
Sphingosine-1-phosphate promotes the differentiation of adipose-derived stem cells into endothelial nitric oxide synthase (eNOS) expressing endothelial-like cells. [PDF]
, 2014 BACKGROUND: Adipose tissue provides a readily available source of autologous stem cells. Adipose-derived stem cells (ASCs) have been proposed as a source for endothelial cell substitutes for lining the luminal surface of tissue engineered bypass grafts ...
Arya, Divya +4 more
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Stem Cell Reports, 2019 Summary: Exogenous cues involved in the regulation of the initial steps of lymphatic endothelial development remain largely unknown. We have used an in vitro model based on the co-culture of vascular precursors derived from mouse embryonic stem cell (ESC)
Mariela Subileau +6 more
doaj +1 more source
In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis [PDF]
, 2014 Although hematopoietic precursor activity can be generated in vitro from human embryonic stem cells, there is no solid evidence for the appearance of multipotent, self-renewing and transplantable hematopoietic stem cells.
De Bleser, Dominique +13 more
core +3 more sources
Endothelial cells mediate the regeneration of hematopoietic stem cells
Stem Cell Research, 2010 Recent studies suggest that endothelial cells are a critical component of the normal hematopoietic microenvironment. Therefore, we sought to determine whether primary endothelial cells have the capacity to repair damaged hematopoietic stem cells. Highly purified populations of primary CD31(+) microvascular endothelial cells isolated from the brain or ...
Shuguang Jiang +5 more
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Stem and endothelial progenitor cells in erection biology [PDF]
International Journal of Impotence Research, 2008 Erectile dysfunction (ED) is defined as the consistent inability to obtain or maintain an erection for satisfactory sexual relations. The past 20 years of basic science research on erection physiology has been devoted to investigating the pathogenesis of ED and has led to the conclusion that ED is predominately a disease of vascular origin with ...
Trinity J. Bivalacqua +4 more
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Measurement of Mesenchymal Stem Cells Attachment to Endothelial Cells
BIO-PROTOCOL, 2018 Mesenchymal stem cells (MSCs) have shown profound therapeutic potential in tissue repair and regeneration. However, recent studies indicate that MSCs are largely entrapped in lungs after intravenous delivery and die shortly. The underlying mechanisms have been poorly understood. We have provided evidence to show that excess expression and activation of
Chris D. Madsen, Shan Wang, Yaojiong Wu
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Angiogenic potential of endothelial progenitor cells and embryonic stem cells [PDF]
Vascular Cell, 2011 Endothelial progenitor cells (EPCs) are implicated in a range of pathological conditions, suggesting a natural therapeutic role for EPCs in angiogenesis. However, current angiogenic therapies involving EPC transplantation are inefficient due to rejection of donor EPCs.
Peter C Rae +6 more
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Effects of shear stress on differentiation of stem cells into endothelial cells
World Journal of Stem Cells, 2021 Stem cell transplantation is an appealing potential therapy for vascular diseases and an indispensable key step in vascular tissue engineering. Substantial effort has been made to differentiate stem cells toward vascular cell phenotypes, including endothelial cells (ECs) and smooth muscle cells.
Jia-Yi Qian +3 more
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