Results 31 to 40 of about 1,444,041 (282)

Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia [PDF]

open access: yes, 2006
Background— Stem and progenitor cell therapy is a novel approach to improve neovascularization and function of ischemic tissue. Enhanced tissue expression of chemoattractant factors such as stromal cell–derived factor 1 and vascular endothelial growth ...
Aicher, A   +5 more
core   +1 more source

Generation of Functional Blood Vessels from a Single c-kit+ Adult Vascular Endothelial Stem Cell

open access: yesPLoS Biology, 2012
Adult vascular endothelial stem cells are shown to reside in the blood vessel wall endothelium. When isolated, these cells are capable of clonal expansion and generate functional blood vessels in vivo.
Shentong Fang   +4 more
semanticscholar   +1 more source

Embryonic endothelial evolution towards first hematopoietic stem cells revealed by single-cell transcriptomic and functional analyses

open access: yesCell Research, 2020
Hematopoietic stem cells (HSCs) in adults are believed to be born from hemogenic endothelial cells (HECs) in mid-gestational embryos. Due to the rare and transient nature, the HSC-competent HECs have never been stringently identified and accurately ...
Siyuan Hou   +17 more
semanticscholar   +1 more source

Insulin-like growth factors promote vasculogenesis in embryonic stem cells. [PDF]

open access: yesPLoS ONE, 2012
The ability of embryonic stem cells to differentiate into endothelium and form functional blood vessels has been well established and can potentially be harnessed for therapeutic angiogenesis.
Stephanie M Piecewicz   +5 more
doaj   +1 more source

eNOS transfection of adipose-derived stem cells yields bioactive nitric oxide production and improved results in vascular tissue engineering. [PDF]

open access: yes, 2015
This study evaluates the durability of a novel tissue engineered blood vessel (TEBV) created by seeding a natural vascular tissue scaffold (decellularized human saphenous vein allograft) with autologous adipose-derived stem cells (ASC) differentiated ...
Bagameri, Gabor   +10 more
core   +2 more sources

Testicular endothelial cells are a critical population in the germline stem cell niche

open access: yesNature Communications, 2018
Maintenance of adult tissues depends on stem cell self-renewal in local niches. Spermatogonial stem cells (SSC) are germline adult stem cells necessary for spermatogenesis and fertility.
D. Bhang   +14 more
semanticscholar   +1 more source

Human embryonic stem cell-derived exosomes promote pressure ulcer healing in aged mice by rejuvenating senescent endothelial cells

open access: yesStem cell research & therapeutics, 2019
Angiogenesis, as an endogenous repair mechanism, plays crucial roles in wound healing and tissue regeneration. However, this process is impaired in the elderly due to aging-related vascular endothelial dysfunction. This study was aimed to explore the pro-
Bi Chen   +8 more
semanticscholar   +1 more source

Distinct role of autophagy on angiogenesis: highlights on the effect of autophagy in endothelial lineage and progenitor cells

open access: yesStem Cell Research & Therapy, 2018
Autophagy plays a critical role in the dynamic growth of each cell through different conditions. It seems that this intracellular mechanism acts as a two-edged sword against the numerous cell insults. Previously, autophagy was described in the context of
Mehdi Hassanpour   +4 more
doaj   +1 more source

Differentiated adipose-derived stem cell cocultures for bone regeneration in polymer scaffolds in vivo. [PDF]

open access: yes, 2014
Critical-sized bone defects can lead to significant morbidity, and interventions are limited by the availability and donor-site morbidity of bone grafts. Polymer scaffolds seeded with cells have been explored to replace bone grafts.
Chang, Shiliang   +8 more
core   +2 more sources

Vascular endothelial growth factor mediates the therapeutic efficacy of mesenchymal stem cell-derived extracellular vesicles against neonatal hyperoxic lung injury

open access: yesExperimental and Molecular Medicine, 2018
We previously reported the role of vascular endothelial growth factor (VEGF) secreted by mesenchymal stem cells (MSCs) in protecting against neonatal hyperoxic lung injuries.
S. Ahn   +6 more
semanticscholar   +1 more source

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