Results 31 to 40 of about 1,271,424 (340)
Cell Research, 2020 Hematopoietic stem cells (HSCs) in adults are believed to be born from hemogenic endothelial cells (HECs) in mid-gestational embryos. Due to the rare and transient nature, the HSC-competent HECs have never been stringently identified and accurately ...
Siyuan Hou +17 more
semanticscholar +1 more source
Testicular endothelial cells are a critical population in the germline stem cell niche
Nature Communications, 2018 Maintenance of adult tissues depends on stem cell self-renewal in local niches. Spermatogonial stem cells (SSC) are germline adult stem cells necessary for spermatogenesis and fertility.
D. Bhang +14 more
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Differentiation of pluripotent stem cells into endothelial cells [PDF]
Current Opinion in Hematology, 2015 Methods to isolate endothelial cells from murine and human pluripotent stem cells continue to evolve and increasingly diverse endothelial cell populations have been generated. This review provides an update of key articles published within the past year that report on some of those advances.Cooperative interactions among microRNA (miRNA), transcription
openaire +4 more sources
Insulin-like growth factors promote vasculogenesis in embryonic stem cells. [PDF]
PLoS ONE, 2012 The ability of embryonic stem cells to differentiate into endothelium and form functional blood vessels has been well established and can potentially be harnessed for therapeutic angiogenesis.
Stephanie M Piecewicz +5 more
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Stem cell research & therapeutics, 2019 Angiogenesis, as an endogenous repair mechanism, plays crucial roles in wound healing and tissue regeneration. However, this process is impaired in the elderly due to aging-related vascular endothelial dysfunction. This study was aimed to explore the pro-
Bi Chen +8 more
semanticscholar +1 more source
Transdifferentiation of cancer stem cells into endothelial cells [PDF]
Open Life Sciences, 2011 Abstract Vasculogenic mimicry was first described as the unique ability of aggressive melanoma cells to express an endothelial phenotype and to form vessel-like networks in three dimensional cultures, “mimicking” the pattern of embryonic vascular networks and recapitulating the patterned networks seen in patients with aggressive tumors ...
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Stem Cell Research & Therapy, 2018 Autophagy plays a critical role in the dynamic growth of each cell through different conditions. It seems that this intracellular mechanism acts as a two-edged sword against the numerous cell insults. Previously, autophagy was described in the context of
Mehdi Hassanpour +4 more
doaj +1 more source
Experimental and Molecular Medicine, 2018 We previously reported the role of vascular endothelial growth factor (VEGF) secreted by mesenchymal stem cells (MSCs) in protecting against neonatal hyperoxic lung injuries.
S. Ahn +6 more
semanticscholar +1 more source
Stem Cells Translational Medicine, 2018 Endothelial cells (ECs) play a key role in revascularization within regenerating tissue. Stem cells are often used as an alternative cell source when ECs are not available.
Guihua Liu +9 more
semanticscholar +1 more source
Endothelial cells mediate the regeneration of hematopoietic stem cells
Stem Cell Research, 2010 Recent studies suggest that endothelial cells are a critical component of the normal hematopoietic microenvironment. Therefore, we sought to determine whether primary endothelial cells have the capacity to repair damaged hematopoietic stem cells. Highly purified populations of primary CD31(+) microvascular endothelial cells isolated from the brain or ...
Shuguang Jiang +5 more
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