Results 51 to 60 of about 1,444,041 (282)

Effects of shear stress on differentiation of stem cells into endothelial cells

open access: yesWorld Journal of Stem Cells, 2021
Stem cell transplantation is an appealing potential therapy for vascular diseases and an indispensable key step in vascular tissue engineering. Substantial effort has been made to differentiate stem cells toward vascular cell phenotypes, including endothelial cells (ECs) and smooth muscle cells.
Jia-Yi Qian   +3 more
openaire   +3 more sources

Induction of spontaneous neo-angiogenesis and tube formation in human endometrial stem cells by bioglass [PDF]

open access: yes, 2015
Endothelial dysfunction is a broad pathological disorder of the endothelium (innermost layer of blood vessels) which is assigned by vasoconstriction, thrombosis and ischemic diseases, alone or with other disorders such as coronary artery disease ...
Ai, Jafar.   +3 more
core   +1 more source

Aging impairs the ability of vascular endothelial stem cells to generate endothelial cells in mice

open access: yesAngiogenesis, 2023
AbstractTissue-resident vascular endothelial stem cells (VESCs), marked by expression of CD157, possess long-term repopulating potential and contribute to vascular regeneration and homeostasis in mice. Stem cell exhaustion is regarded as one of the hallmarks of aging and is being extensively studied in several types of tissue-resident stem cells ...
Shimizu, Shota   +7 more
openaire   +2 more sources

IFNα-mediated remodeling of endothelial cells in the bone marrow niche

open access: yesHaematologica, 2017
In the bone marrow, endothelial cells are a major component of the hematopoietic stem cell vascular niche and are a first line of defense against inflammatory stress and infection.
Áine M. Prendergast   +5 more
doaj   +1 more source

Efficient Generation of Human Embryonic Stem Cell-Derived Corneal Endothelial Cells by Directed Differentiation

open access: yesPLoS ONE, 2015
Aim To generate human embryonic stem cell derived corneal endothelial cells (hESC-CECs) for transplantation in patients with corneal endothelial dystrophies.
K. McCabe   +5 more
semanticscholar   +1 more source

Transition of mesenchymal stem/stromal cells to endothelial cells [PDF]

open access: yesStem Cell Research & Therapy, 2013
Mesenchymal stem/stromal cells (MSCs) are heterogeneous. A fraction of these cells constitute multipotent cells that can self-renew and mainly give rise to mesodermal lineage cells such as adipocytes, osteocytes and chondrocytes. The ability of MSCs to differentiate into endothelial cells remains controversial.
openaire   +3 more sources

A Mesoderm-Derived Precursor for Mesenchymal Stem and Endothelial Cells [PDF]

open access: yesCell Stem Cell, 2010
Among the three embryonic germ layers, the mesoderm is a major source of the mesenchymal precursors giving rise to skeletal and connective tissues, but these precursors have not previously been identified and characterized. Using human embryonic stem cells directed toward mesendodermal differentiation, we show that mesenchymal stem/stromal cells (MSCs)
Junying Yu   +7 more
openaire   +3 more sources

From bedside to the bench: patient-specific hiPSC-EC models uncover endothelial dysfunction in genetic cardiomyopathies

open access: yesFrontiers in Physiology, 2023
Genetic cardiomyopathies are a group of inherited disorders in which myocardial structure and function are damaged. Many of these pathologies are rare and present with heterogenous phenotypes, thus personalized models are required to completely uncover ...
Martina Rabino   +6 more
doaj   +1 more source

Improved arteriogenesis with simultaneous skeletal muscle repair in ischemic tissue by SCL plus multipotent adult progenitor cell clones from peripheral blood [PDF]

open access: yes, 2004
Background: The CD34- murine stem cell line RM26 cloned from peripheral blood mononuclear cells has been shown to generate hematopoietic progeny in lethally irradiated animals.
Gottgens, Berthold   +7 more
core   +1 more source

Angiogenic and Immunomodulatory Properties of Endothelial and Mesenchymal Stem Cells [PDF]

open access: yesTissue Engineering Part A, 2016
It has been suggested that the effect of implanted cells on the local environment is important when selecting the appropriate cell type for tissue regeneration. Our aim was to compare the local tissue response to implanted human mesenchymal stem cells (MSC) and human umbilical vein endothelial cells (EC). MSC and EC were cultured in poly(L-lactide-co-1,
Bartaula-Brevik, Sushma   +4 more
openaire   +5 more sources

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