Journal of Lipid Research, 2005 There is some controversy regarding whether vascular responses to endothelin are altered in hypercholesterolemia. Studies performed to date have been compromised by the use of endothelin antagonists at inappropriate concentrations.
Lauren M. Boak +3 more
doaj +1 more source
Role of endothelin-1 in periodontal diseases: A structured review
Indian Journal of Dental Research, 2016 Background and Objective: Endothelin-1 (ET-1) is a 21-amino acid peptide and is a potent vasoconstrictor produced by endothelial cells. It plays a role in the development of diseases such as hypertension and atherosclerosis.
Waleed Khalid +4 more
semanticscholar +1 more source
Anti-adrenergic effects of endothelin on human atrial action potentials are potentially anti-arrhythmic [PDF]
, 2006 Endothelin-1 (ET-1) is elevated in patients with atrial fibrillation (AF) and heart failure. We investigated effects of ET-1 on human atrial cellular electrophysiological measurements expected to influence the genesis and maintenance of AF.
Kane, K.A. +3 more
core +1 more source
Effects of magnesium treatment in a model of internal capsule lesion in spontaneously hypertensive rats [PDF]
, 2008 <p><b>Background and Purpose:</b> The study aim was to assess the effects of magnesium sulfate (MgSO4) administration on white matter damage in vivo in spontaneously hypertensive rats.</p> <p><b>Methods:</b> ...
Gallagher, L. +8 more
core +1 more source
The Structural Features of Vascular Endothelium in Acute Cerebral Ischemia [PDF]
, 2017 The aim of the research was to study the number and structural properties of desquamated endothelial cells (DECs) in the peripheral blood in carotid ischemic stroke (CIS) and carotid transient ischemic attacks (TIAs) and its connection with the marker of
Kosheleva, A. (Anna)
core +2 more sources
Expression of endothelin-1 in unaffected colon mucosa 10 cm and 20 cm from colorectal carcinoma [PDF]
Medicinski PodmladakIntroduction: Endothelin-1 is a vasoconstrictor peptide primarily synthesized by endothelial and smooth muscle cells. Increased expression of this peptide has been observed in inflammation, hypoxia, ischemia, various cardiovascular diseases and various ...
Stanojlović Anja, Despotović Sanja
doaj +1 more source
Myocardial ischemia-reperfusion enhances transcriptional expression of endothelin-1 and vasoconstrictor ETB receptors via the protein kinase MEK-ERK1/2 signaling pathway in rat. [PDF]
PLoS ONE, 2017 BACKGROUND:Coronary artery remodelling and vasospasm is a complication of acute myocardial ischemia and reperfusion. The underlying mechanisms are complex, but the vasoconstrictor peptide endothelin-1 is suggested to have an important role.
Gry Freja Skovsted +5 more
doaj +1 more source
Small Vessel Disease in the Heart and Brain: Current Knowledge, Unmet Therapeutic Need and Future Directions [PDF]
, 2019 No abstract ...
Berry, C +6 more
core +2 more sources
Endothelin-1 contributes to the development of virus-induced demyelinating disease
Journal of Neuroinflammation, 2020 Background Experimental autoimmune encephalitis (EAE) and virally induced demyelinating disease are two major experimental model systems used to study human multiple sclerosis.
Young-Hee Jin +4 more
doaj +1 more source
Endothelin receptor B antagonists decrease glioma cell viability independently of their cognate receptor [PDF]
, 2008 Background: Endothelin receptor antagonists inhibit the progression of many cancers, but research into their influence on glioma has been limited. Methods: We treated glioma cell lines, LN-229 and SW1088, and melanoma cell lines, A375 and WM35 ...
A Bagnato +42 more
core +3 more sources