Results 71 to 80 of about 24,309,158 (381)

Automating Vascular Biology: An End‐to‐End Automated Workflow for High‐Throughput Blood Vessel‐on‐a‐Chip Production and Multi‐Site Validation

open access: yesAdvanced Healthcare Materials, EarlyView.
AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin   +14 more
wiley   +1 more source

Inverse correlation between endothelin-1-induced peripheral microvascular vasoconstriction and blood pressure in glaucoma patients [PDF]

open access: yes, 2018
• Background: The potent vasoconstrictor peptide endothelin-I has been shown to participate in the control of peripheral vascular tone and in the regulation of ocular perfusion.
Flammer, Josef   +5 more
core  

The effect of ethnicity on the vascular responses to cold exposure of the extremities [PDF]

open access: yes, 2014
This is an accepted manuscript of an article published by Springer in European Journal of Applied Physiology on 01/08/2014, available online: https://doi.org/10.1007/s00421-014-2962-2 The accepted version of the publication may differ from the final ...
Eglin, CM   +3 more
core   +3 more sources

The role of the biomarker and the genetic polymorphism of endothelin-1 in pulmonary arterial hypertension among Egyptians

open access: yesEgyptian Journal of Chest Disease and Tuberculosis, 2012
Study objective: This study analyses for the first time endothelin-1 (ET-1) level, and gene polymorphisms for endothelin-1 (EDN1 gene) in patients with pulmonary arterial hypertension (PAH) in Egypt. Design: Cross-sectional study.
Emad Ibrahim   +2 more
doaj   +1 more source

Membrane depolarization is required for pressure-dependent pulmonary arterial tone but not enhanced vasoconstriction to endothelin-1 following chronic hypoxia

open access: yesPulmonary Circulation, 2020
Enhanced vasoconstriction is increasingly identified as an important contributor to the development of pulmonary hypertension. Chronic hypoxia results in enhanced Rho kinase mediated Ca 2+ sensitization contributing to pressure-dependent pulmonary ...
Charles E Norton   +3 more
doaj   +1 more source

Endothelin-1 and osteoblastic metastasis [PDF]

open access: yesProceedings of the National Academy of Sciences, 2003
When cancer metastasizes to distant sites, it essentially forms an army of occupation. Just as the presence of an army of occupation alters the behavior of the preexisting resident population, the resident host cells react in a variety of ways to the presence of the metastatic cancer cells.
openaire   +2 more sources

Endothelin-1, aging and hypertension [PDF]

open access: yesCurrent Opinion in Cardiology, 2008
Endothelin-1 system activation plays an important role in the etiology of atherosclerotic vascular disease. Aging and hypertension are two independent cardiovascular risk factors that have been shown to exhibit increased endothelin-1 system activation. This review focuses on the cardiovascular effects of the endothelin system, its relation to aging and
Brian L, Stauffer   +2 more
openaire   +2 more sources

The Role of Endothelin-1 and Endothelin Receptor Antagonists in Inflammatory Response and Sepsis

open access: yesArchivum Immunologiae et Therapiae Experimentalis, 2014
Endothelin-1 (ET-1) is a potent endogenous vasoconstrictor, mainly secreted by endothelial cells. It acts through two types of receptors: ETA and ETB.
A. Kowalczyk   +4 more
semanticscholar   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang   +4 more
wiley   +1 more source

Modulation of endothelin-1-induced contractions by magnesium/calcium in porcine ciliary arteries [PDF]

open access: yes, 2018
• Background: The present study was performed to investigate the influence of extracellular magnesium on changes in contractile tone induced by endothelin-1, and on relaxations to bradykinin in isolated porcine ciliary arteries.
Dettmann, Eike   +3 more
core  

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