Results 151 to 160 of about 283,023 (320)

Amelioration of glyceril-induced acute renal failure in rats by an endothelin a receptor antagonist (S-0139)

, 1997
Toshikatsu Shimizu, Takayuki Kuroda, Satoshi Hata, Masafumi Fujimoto   +3 more
openalex   +1 more source

Effects of combined treatment with zibotentan and dapagliflozin compared to dapagliflozin alone in patients with diabetic and non‐diabetic chronic kidney disease

Diabetes, Obesity and Metabolism, Volume 27, Issue 8, Page 4311-4319, August 2025.
Abstract Aims To evaluate whether type 2 diabetes status modifies the efficacy and safety of combining zibotentan (zibo), a selective endothelin receptor antagonist, and dapagliflozin (dapa) compared to placebo plus dapagliflozin in individuals with chronic kidney disease (CKD).
Victor Wasehuus, J. David Smeijer, Phil Ambery, Peter J. Greasley, Emma Wijkmark, David C. Wheeler, Peter Rossing, Hiddo J. L. Heerspink   +7 more
wiley   +1 more source

A non-selective endothelin receptor antagonist bosentan modulates kinetics of bone marrow-derived cells in ameliorating pulmonary hypertension in mice. [PDF]

Pulm Circ, 2020
Kato T, Mitani Y, Masuya M, Maruyama J, Sawada H, Ohashi H, Ikeyama Y, Otsuki S, Yodoya N, Shinohara T, Miyata E, Zhang E, Katayama N, Shimpo H, Maruyama K, Komada Y, Hirayama M.   +16 more
europepmc   +1 more source

Therapy with the Nonpeptide Endothelin Receptor Antagonist 97-139 in a Murine Model of Congestive Heart Failure. Reduction of Cardiac Mass and Myofiber Hypertrophy.

, 2000
Yukihiro Seta, Tsugiyasu Kanda, T Yokoyama, Masashi Arai, Kenichi Sekiguchi, Tohru Tanaka, Isao Kobayashi, Ryozo Nagai   +7 more
openalex   +2 more sources

Effects of gestational intermittent hypoxia on the respiratory system: A tale of the placenta, fetus, and developing offspring

Journal of Sleep Research, Volume 34, Issue 4, August 2025.
Effects of gestational intermittent hypoxia on maternal, fetal and offspring respiratory system. In black, effects in humans; in red, in vitro effects; in blue, effects in animal models. Summary Obstructive sleep apnea (OSA) is a common sleep disorder that is associated with a wide variety of health conditions, including cardiovascular, cerebrovascular,
Esther Valverde‐Pérez, Elena Olea, Asunción Rocher, Philip I. Aaronson, Jesús Prieto‐Lloret   +4 more
wiley   +1 more source

Early Response in Albuminuria and Long-Term Kidney Protection during Treatment with an Endothelin Receptor Antagonist: A Prespecified Analysis from the SONAR Trial.

J Am Soc Nephrol, 2021
Heerspink HJL, Xie D, Bakris G, Correa-Rotter R, Hou FF, Kitzman DW, Kohan D, Makino H, McMurray JJV, Perkovic V, Rossing P, Parving HH, de Zeeuw D, on behalf on the SONAR Investigators.   +13 more
europepmc   +1 more source

Organocatalytic Enantioselective Conjugate Addition of Nitromethane to Benzylidene-2-Benzoyl Acetate: Asymmetric Synthesis of ABT - 627, an Endothelin Receptor Antagonist. [PDF]

Front Chem, 2020
Hajra S, Aziz SM, Jana B, Hazra S.
europepmc   +1 more source

The Endothelin-A-Receptor Antagonist PD180988 (CI-1034) Selectively Reverses the Pulmonary Vasoconstrictor Response to Hypoxia in the Lamb

, 2000
Yashu Coe, Stephen J. Haleen, Kathleen M. Welch, Flavio Coceani   +3 more
openalex   +1 more source

Protective Effect of Endothelin Type A Receptor Antagonist on Brain Edema and Injury After Transient Middle Cerebral Artery Occlusion in Rats [PDF]

, 2001
Yoshiyuki Matsuo, Shin‐ichi Mihara, Mitsuyoshi Ninomiya, Masafumi Fujimoto   +3 more
openalex   +1 more source

The endothelin receptor antagonist bosentan improves peripheral endothelial function in patients with type 2 diabetes mellitus and microalbuminuria: a randomised trial

Diabetologia, 2012
A. Rafnsson, F. Böhm, M. Settergren, A. Gonon, K. Brismar, J. Pernow   +5 more
semanticscholar   +1 more source