Results 131 to 140 of about 285,474 (314)
Environmental modulators of vascular physiology and inflammation
Experimental Physiology, Volume 111, Issue 2, Page 321-334, 1 February 2026.Abstract Environmental factors play a crucial role in modulating vascular inflammation, contributing significantly to the development of atherosclerosis and cardiovascular disease. This review synthesizes current evidence on how various environmental exposures influence vascular function and inflammation, with a focus on pollutants such as particulate ...
Anusha N. Seneviratne +3 more
wiley +1 more source
Current Challenges in Hemostasis and Advances in Particle‐Assisted Styptic Devices
Advanced Healthcare Materials, Volume 15, Issue 2, 14 January 2026.Here persistent limitations in hemostatic technologies are highlighted and cutting‐edge biomimetic, microparticle‐assisted, and nanoengineered systems with integrated drug delivery are showcased. Moreover, the article identifies fresh directions toward the next‐generation of multifunctional hemostatic devices with superior efficacy and accessibility ...
Daniele Baiocco +4 more
wiley +1 more source
Терапевтический архив, 2013 The paper reviews current views of the problem of pulmonary hypertension. It shows the classification of pulmonary hypertension and considers the general issues of its pathogenesis, morphological changes, clinical picture, and main approaches to treating
N A Tsareva
doaj
Advanced Science, Volume 13, Issue 5, 27 January 2026.This study demonstrates that tumor‐derived IL‐35 promotes pancreatic cancer fibrosis by indirectly activating pancreatic stellate cells through IGFBP2/IGF‐1R/PI3K‐Akt and Tsp‐1/TGF‐β pathways. IL‐35 blockade reduces stromal fibrosis, restores chemosensitivity, and synergizes with gemcitabine‐based regimens, highlighting IL‐35 as a promising therapeutic
Hui Li +14 more
wiley +1 more source
Endothelin-Receptor Antagonists beyond Pulmonary Arterial Hypertension: Cancer and Fibrosis.
Journal of Medicinal Chemistry, 2016 J. Aubert, L. Juillerat-Jeanneret
semanticscholar +1 more source
The pharmacokinetic profile of sitaxsentan, a selective endothelin receptor antagonist, in varying degrees of renal impairment [PDF]
, 2007 Neeraj Dhaun +7 more
openalex +1 more source
Cancer Medicine, Volume 15, Issue 1, January 2026.ABSTRACT Background Adiposity‐Based Chronic Disease (ABCD), a novel model housing obesity, insulin resistance, and adipokine‐related inflammation, increases the risk of aggressive prostate cancer (PCa), posttreatment PCa recurrence, and PCa mortality. This paper provides a new network analysis of relevant metabolic drivers to provide insight into the ...
Zachary Dovey +2 more
wiley +1 more source
Effects of a novel endothelin ETB receptor antagonist, RES-701-1, on isolated blood vessels.
, 1994 Hideaki Karaki +4 more
openalex +1 more source
A Case of Atrial Septal Defect Unveiled by the Treatment for Pulmonary Arterial Hypertension
Clinical Case Reports, Volume 14, Issue 1, January 2026.ABSTRACT We present a case of a 51‐year‐old woman with atrial septal defect (ASD) masked by pulmonary arterial hypertension (PAH). Three months after PAH treatment with a combination of endothelin receptor antagonist and phosphodiesterase five inhibitor, the transthoracic echocardiography revealed left‐to‐right shunting through a secundum ASD.
Takaaki Fujii +12 more
wiley +1 more source