Results 141 to 150 of about 285,474 (314)

Edible Seeds in the Fight Against Hypertension: A Review of In Vitro, In Vivo, and Clinical Evidences With a Mechanistic Insight of Bioactive Compounds

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
The presented review provides the potential antihypertensive benefits of traditionally employed edible seeds, presenting new perspectives and avenues for future research. ABSTRACT Hypertension, often referred to as a silent killer, is responsible for 7.5 million deaths, representing approximately 12.8% of all global mortality.
Jinmin Shi   +8 more
wiley   +1 more source

A review of pulmonary arterial hypertension: role of ambrisentan

open access: yesVascular Health and Risk Management, 2007
Robyn J BarstColumbia University College of Physicians & Surgeons, New York, NY, USAAbstract: Pulmonary arterial hypertension (PAH) is a rare fatal disease.
Robyn J Barst
doaj  

Endothelin receptor antagonists for pulmonary arterial hypertension and COVID-19: Friend or foe? [PDF]

open access: yesJ Heart Lung Transplant, 2020
Badagliacca R, Sciomer S, Petrosillo N.
europepmc   +1 more source

Multiple Compound-Related Adverse Properties Contribute to Liver Injury Caused by Endothelin Receptor Antagonists

open access: yesJournal of Pharmacology and Experimental Therapeutics, 2015
J. G. Kenna   +9 more
semanticscholar   +1 more source

The biased apelin receptor agonist, MM07, reverses Sugen/hypoxia-induced pulmonary arterial hypertension as effectively as the endothelin antagonist macitentan [PDF]

open access: gold
Thomas Williams   +6 more
openalex   +1 more source

P16‐69: Assessment of the effect of endothelin receptor antagonist in patients with less severe or severe pulmonary hypertension associated with interstitial lung disease [PDF]

open access: bronze, 2021
Susumu Sakamoto   +28 more
openalex   +1 more source

Curcumin Protected CoCl2‐Induced Apoptosis and Ferroptosis in Human Umbilical Vein Endothelial Cells by Regulating the Expression of HSPA6

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
Curcumin reduces the expression of MMP1 and MMP13 while increasing TIMP‐1 levels by downregulating HSPA6 in CoCl2‐induced HUVECs. This mechanism attenuates apoptosis, ferroptosis, and mitochondrial damage in HUVECs. These findings suggest that curcumin holds promise for the clinical treatment of hypoxia‐induced vascular diseases.
Ruihai Ye   +5 more
wiley   +1 more source

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