Results 101 to 110 of about 87,171 (374)

ETB receptor protects the tubulointerstitium in experimental thrombotic microangiopathy [PDF]

, 2002
ETB receptor protects the tubulointerstitium in experimental thrombotic microangiopathy.BackgroundThe characteristic features of thrombotic microangiopathy (TMA) include glomerular and peritubular capillary endothelial cell injury with thrombus formation
Fujita, Toshiro, Gariepy, Cheryl E., Inagi, Reiko, Johnson, Richard J., Kurokawa, Kiyoshi, Miyata, Toshio, Nangaku, Masaomi, Yamada, Koei, Yanagisawa, Masashi   +8 more
core   +1 more source

SPARCL1 and NT‐proBNP as biomarkers of right ventricular‐to‐pulmonary artery uncoupling in pulmonary hypertension

ESC Heart Failure, Volume 12, Issue 2, Page 1416-1426, April 2025.
Abstract Aims SPARCL1 was recently identified as a biomarker of right ventricular (RV) maladaptation in patients with pulmonary hypertension (PH), and N‐terminal pro‐brain natriuretic protein (NT‐proBNP) is an established biomarker of RV failure in PH. The present study investigated whether NT‐proBNP and SPARCL1 concentrations are associated with load ...
Oliver Dörr, Stanislav Keranov, Paulina van Wickern, Holger Nef, Christian Hamm, Pascal Bauer, Christian Troidl, Samuel Sossalla, Sandra Voss, Christoph Liebetrau, Manuel J. Richter, Henning Gall, Werner Seeger, Ardeschir Ghofrani, Athiththan Yogeswaran, Khodr Tello   +15 more
wiley   +1 more source

Endothelin-1 Induced Vascular Smooth Muscle Cell Proliferation is Mediated by Cytochrome P-450 Arachidonic Acid Metabolites

Biomolecules & Biomedicine, 2010
Endothelins (ETs) are a family of three peptides (ET-1, ET-2, ET-3) that are implicated in the physiological control of vascular smooth muscle cell (VSMC) and myocardial contractility and growth.
Farid Ljuca, Gorazd Drevenšek
doaj   +1 more source

HERVs, transposons and human diseases : part 3 [PDF]

, 2012
Part 1 and 2 of this article can be found through theses links: https://www.um.edu.mt/library/oar//handle/123456789/12961 https://www.um.edu.mt/library/oar//handle/123456789/13012Part 3 of the article.
Baldacchino, Sandra, Grech, Alfred
core   +1 more source

Role for inflammatory markers in predicting right ventricular failure in mechanical assist device recipients

ESC Heart Failure, EarlyView.
Abstract Right ventricular failure (RVF) is a common complication following left ventricular assist device (LVAD) implantation and increases patient morbidity and mortality. Due to the complex and limited understanding of RVF pathophysiology, efforts to prognosticate RVF after LVAD have been challenging.
Abdul‐Fatawu Osman, Shane S. Scott, Ebubechukwu O. Ezeh, Evans Osuji, Israel O. Ailemen, Mohamed H. Derbala, Salil Kumar, Asvin M. Ganapathi, Daniel B. Sims, Ashrith Guha, Bryan A. Whitson, Sakima A. Smith   +11 more
wiley   +1 more source

Pulmonary vasodilation in acute pulmonary embolism – a systematic review

Pulmonary Circulation, 2020
Acute pulmonary embolism is the third most common cause of cardiovascular death. Pulmonary embolism increases right ventricular afterload, which causes right ventricular failure, circulatory collapse and death.
Mads Dam Lyhne, Jeffrey Allen Kline, Jens Erik Nielsen-Kudsk, Asger Andersen   +3 more
doaj   +1 more source

Measurement of plasma endothelin-1 in experimental hypertension and in healthy subjects [PDF]

, 2017
Background: Endothelin-1 is an endothelium-derived potent vasoconstrictor peptide of 21 amino acids. To establish reference values in different models of hypertension and in human subjects an assay for plasma immunoreactive endothelin-1 (ET-1) was ...
Abdel-Sayed, Saad, Aubert, Jean-François, Brakch, Noureddine, Brunner, Hans Rudolf, Gohlke, Peter, Nussberger, Juerg   +5 more
core  

Mono and combination therapies in pulmonary arterial hypertension patients with comorbidities: A COMPERA analysis

ESC Heart Failure, EarlyView.
AIM This analysis provides a comparison of the efficacy of initial mono and combination therapy in patients with PAH and cardiovascular comorbidities or with risk factors of HFpEF (heart failure with preserved ejection fractioin).METHOD Data from the European COMPERA registry were used for a matched pair analysis.
Dirk Skowasch, Christine Pausch, Doerte Huscher, David Pittrow, Judith Wede, Fabian Kreimendahl, Stephan Rosenkranz, Stephan Beckmann, Matthias Held, Ekkehard Grünig, H. Ardeschir Ghofrani, Hans Klose, Andris Skride, Michael Halank, Stefan Stadler, Marion Delcroix, Anton Vonk‐Noordegraaf, Ralf Ewert, Grzegorz Kopec, Marius M. Hoeper, Karen M. Olsson   +20 more
wiley   +1 more source

Brachial Artery Constriction during Brachial Artery Reactivity Testing Predicts Major Adverse Clinical Outcomes in Women with Suspected Myocardial Ischemia: Results from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study [PDF]

, 2013
Background:Limited brachial artery (BA) flow-mediated dilation during brachial artery reactivity testing (BART) has been linked to increased cardiovascular risk.
Bairey Merz, CN, Johnson, BD, Pepine, CJ, Reis, SE, Sedlak, TL   +4 more
core   +1 more source

The effects of early exercise on cardiovascular biomarkers in patients with congestive heart failure

ESC Heart Failure, EarlyView.
Abstract Background Exercise training improves functional outcomes in chronic heart failure (HF), but the effects of early in‐hospital physical activity on cardiovascular biomarkers and prognosis in acute congestive heart failure (AHF) patients remain unclear.
Yanxiang Sun, Xuansheng Huang, Bing Hu, Zidi Wu, Yanchun Zhang, Yong Yuan, Li Feng   +6 more
wiley   +1 more source