Results 271 to 280 of about 87,171 (374)
Lactate, beyond a metabolic byproduct, regulates immunity and inflammation, linked to cardiovascular diseases (CVD) via metabolic reprogramming. Lactylation, a lactate‐driven epigenetic mark, modulates gene expression in fibrosis, lipid disorders, and CVD progression.
Mengyang Song+3 more
wiley +1 more source
Endothelin in renal disease: role of endothelin antagonists [PDF]
Lüscher, T. F., Wenzel, R. R.
core
Efficient Regioselective Iodination of Pyrazole Derivatives Mediated by Cadmium(II) Acetate
The iodination reactions of both N, C alkyl‐, propargylic substituted and unsubstituted pyrazole derivatives initiated by cadmium (II) acetate were performed. It was revealed that the C‐4 position of the pyrazole ring was more nucleophilic. The nucleophilicity of the pyrazole ring significantly increased due to the influence of alkyl groups and ...
Nina G. Hobosyan+8 more
wiley +1 more source
Aprocitentan in hypertension management: clinical efficacy, safety, and future prospects. [PDF]
Riaz R+6 more
europepmc +1 more source
A Patient With Pulmonary Hypertension Carrying FLNA Loss‐of‐Function Variant
Abstract In a recent study conducted by Laura Stourm et al., the authors identified that patients with pulmonary hypertension (PH) harboring loss‐of‐function variants in the Filamin A (FLNA) gene exhibit a unique spectrum of phenotypes. These include pulmonary involvement with lung parenchymal abnormalities and emphysema, as well as a range of ...
Zongye Cai+9 more
wiley +1 more source
Effect of Tranilast on Endothelin-Induced Bronchoconstriction in Guinea Pigs.
Hiroichi Nagai+3 more
openalex +2 more sources