Results 61 to 70 of about 36,666 (331)

Microvessel density in the placental bed among preeclampsia patients

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Morphological changes in the spiral arteries of the placental bed have been studied in patients with preeclampsia, one of the largest causes of maternal and perinatal morbidity and mortality.
Tarcisio Mota Coelho, Nelson Sass, Luiz Camano, Antonio Fernandes Moron, Rosiane Mattar, João Noberto Stávale, Maria Regina Régis Silva, Marília da Glória Martins, João Nogueira Neto   +8 more
doaj   +1 more source

Regulatory and functional interaction of vasoactive factors in the kidney and extracellular pH [PDF]

, 2004
Regulatory and functional interaction of vasoactive factors in the kidney and extracellular pH. A growing body of evidence suggests that vasoactive factors produced in the kidney such as nitric oxide, endothelins, angiotensin, and prostaglandins ...
Prabhakar, Sharma S.
core   +1 more source

Comprehensive genetic analysis of poorly differentiated gastric cancer in young females

Annals of Gastroenterological Surgery, EarlyView.
Although the involvement of female sex hormones in the development of poorly differentiated gastric cancer in young females is controversial, our detailed analysis using RNA‐seq suggested that the female sex hormone, β‐estradiol plays a role in the development of poorly differentiated gastric cancer in young females. Abstract Aim The reasons behind the
Nobuhiro Nakazawa, Takehiko Yokobori, Yohei Morishita, Akinobu Echigo, Reika Kawabata‐Iwakawa, Akiharu Kimura, Akihiko Sano, Makoto Sakai, Ken Shirabe, Hiroshi Saeki   +9 more
wiley   +1 more source

Cerebral hemodynamics: concepts of clinical importance

Arquivos de Neuro-Psiquiatria, 2012
Cerebral hemodynamics and metabolism are frequently impaired in a wide range of neurological diseases, including traumatic brain injury and stroke, with several pathophysiological mechanisms of injury.
Edson Bor-Seng-Shu, William S. Kita, Eberval G. Figueiredo, Wellingson S. Paiva, Erich T. Fonoff, Manoel J. Teixeira, Ronney B. Panerai   +6 more
doaj   +1 more source

Análise dos níveis de endotelina-1 na saliva de pacientes portadores de carcinoma espinocelular bucal [PDF]

, 2010
Objectives: The present study aimed to verify if the salivary Endothelin-1 (ET-1) expression might represent an efficient biomarker to evaluate risk and prognosis from oral squamous cell carcinoma (OSCC).Methods: For the present study, saliva obtained ...
Hoffmann, Renata da Rocha
core  

Role of heme oxygenase in modulating endothelial function in mesenteric small resistance arteries of spontaneously hypertensive rats. [PDF]

, 2009
It has been proposed that endothelial dysfunction is due to the excessive degradation of nitric oxide (NO) by oxidative stress. The enzyme heme-oxygenase (HO) seems to exert a protective effect on oxidative stress in the vasculature, both in animal ...
Agabiti Rosei E., Boari GE, de Ciuceis C, Favero G, Foglio E, Paiardi S, Platto C, Porteri E, Rezzani R, Rizzardi N, Rizzoni D, Rodella LF   +11 more
core   +1 more source

Absence of Functional Autoantibodies Targeting Angiotensin II Receptor Type 1 and Endothelin‐1 Type A Receptor in Circulation and Purified IgG From Patients With Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Systemic sclerosis (SSc) is a rare but severe autoimmune disease characterized by immune dysregulation, fibrosis, and vasculopathy. Although previous studies have highlighted the presence of functional autoantibodies targeting the angiotensin II receptor type 1 (AT1) and endothelin‐1 type A receptor (ETAR), leading to autoantibody‐mediated ...
Wieke M. van Oostveen, Eva M. Hoekstra, E. W. Nivine Levarht, Ilana B. Kotliar, Thomas P. Sakmar, René E. M. Toes, Jeska K. de Vries‐Bouwstra, Laura H. Heitman, Cynthia M. Fehres   +8 more
wiley   +1 more source

Serum Type I Interferon Score for Prediction of Clinically Meaningful Disease Progression in Limited Cutaneous Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To assess the value of serum type I interferon (IFN) score in predicting clinically meaningful progression in limited cutaneous systemic sclerosis (lcSSc) using a novel composite endpoint adopted from the MINIMISE clinical trial. Methods A retrospective, longitudinal lcSSc cohort was identified within a national, multicenter observational ...
Stefano Di Donato, Rebecca Ross, Ranjitha Karanth, Vishal Kakkar, Enrico De Lorenzis, Lesley‐Anne Bissell, Kristina Clark, Philip Yee, Christopher P. Denton, Francesco Del Galdo   +9 more
wiley   +1 more source

Endothelins and carcinogenesis

Postępy Higieny i Medycyny Doświadczalnej, 2016
Endothelins are a family of four endogenous peptides (ET-1, ET-2, ET-3, ET-4) secreted primarily in an inactive form by the endothelium. They are activated with the participation of converting enzyme. Numerous studies have described their pleiotropic biological activity.
Jacek Olender, Katarzyna Walkiewicz, Małgorzata Muc-Wierzgoń, Ewa Nowakowska-Zajdel   +3 more
openaire   +3 more sources

Activin A‐activated ALK4 induces pathogenic Th17 involved endothelial–mesenchymal transition in systemic lupus erythematosus‐associated pulmonary arterial hypertension

Arthritis &Rheumatology, Accepted Article.
Objective Autoimmune diseases, such as systemic lupus erythematosus (SLE), are associated with pulmonary arterial hypertension (PAH), a condition that can lead to heart failure. However, whether T cells also contribute to the occurrence of PAH in SLE, has not been clarified.
Shuliang Jing, Junyan Qian, Hongjie Ying, Pei Mao, Mingxin Yao, Zhihong Wu, Harm J Bogaard, Lie Wang, Mengtao Li, Jun Yang   +9 more
wiley   +1 more source