Results 91 to 100 of about 3,916 (146)

Glycogen synthase kinase 3 activity enhances liver inflammation in MASH

JHEP Reports
Background & Aims: Metabolic dysfunction-associated steatohepatitis (MASH) is characterized by excessive circulating toxic lipids, hepatic steatosis, and liver inflammation.
Mireille Khoury, Qianqian Guo, Kunimaro Furuta, Cristina Correia, Chady Meroueh, Hyun Se Kim Lee, Khaled Warasnhe, Lucía Valenzuela-Pérez, Andrew P. Mazar, Iljung Kim, Yung-Kyun Noh, Heather Holmes, Michael F. Romero, Caroline R. Sussman, Kevin D. Pavelko, Shahidul Islam, Adebowale O. Bamidele, Petra Hirsova, Hu Li, Samar H. Ibrahim   +19 more
doaj   +1 more source

COVID-19 and the Heart

Methodist DeBakey Cardiovascular Journal, 2021
Mouaz H. Al-Mallah
doaj   +1 more source

Gas-6 Scavenges Anionic Phospholipid-Expressing Microparticles and Mitigates TBI-Induced Endotheliopathy and Coagulopathy in Mice

BACKGROUND: Traumatic brain injury (TBI) results in the release of microparticles from injured brain cells into circulation.
Yichi Zhang, Lujia Tang, Tianrui Ma, Chenyang Liu, Hao Zhang, Pengbo Zhao, Zijian Zhou, Xiangru Ren, Yang Li, Guili Yang, Min Li, Zilong Zhao, Xiaoyang Zhang, Yuyang Miao, Min Wang, Kaifeng Pang, Jing-fei Dong, Yuhua Wang, Yafan Liu   +18 more
core   +1 more source

Uncovering The Role Of Heparanase-Armed Extracellular Vesicles In Sepsis-Associated Vascular Endotheliopathy [PDF]

Sepsis remains one of the most frequent causes of mortality and life-altering morbidity in humans of all ages globally. Though sepsis pathobiology is incompletely understood, it is clear that a unifying feature of all sepsis phenotypes is systemic ...
Richter, Robert Patrick
core  

Endotheliopathy in CAR T-Cell Therapy: Mechanistic Insights into the VWF/ADAMTS13 Axis and the Angiopoietin-Tie2 Pathway. [PDF]

TH Open
de Bruijn S, Vangenechten I, Anguille S, Gadisseur A.   +3 more
europepmc   +1 more source

Endotheliopathy in COVID-19 and Sickle Cell Disease

Background: This thesis examines endotheliopathy in two distinct disease settings; COVID-19 and Sickle Cell Disease (SCD). Coagulation activation and endothelial cell (EC) dysfunction are now well-known features of COVID-19, however our understanding of ...
Helen Fogarty (7899788)
core   +1 more source

Recent Advances in Pathogenesis and Anticoagulation Treatment of Sepsis-Induced Coagulopathy

Journal of Inflammation Research
Chit Man,* Yuan An,* Guo-Xin Wang,* En-Qiang Mao, Li Ma Department of Emergency, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People’s Republic of China*These authors contributed equally to this ...
Man C, An Y, Wang GX, Mao EQ, Ma L
doaj  

Shock Induced Endotheliopathy and High Trauma Mortality-Fight-or-Flight Response Revisited. [PDF]

Int J Mol Sci
Weinstein N, Holcomb JB, Johansson PI.
europepmc   +1 more source

Trauma-Induced Coagulopathy: From Endotheliopathy and Fibrinolysis Phenotypes to Viscoelastic-Guided Resuscitation. [PDF]

Eur J Haematol
Meister R, Kim Y, Landry TC, LaVasseur C, Shatzel J, Deloughery T.   +5 more
europepmc   +1 more source

Defining the Systemic Response to Flight After Polytrauma in a Murine Model. [PDF]

Mil Med
Becker ER, Wetmore GC, Wattley LJ, Price AD, England L, Schuster RM, Pritts TA, Goodman MD.   +7 more
europepmc   +1 more source