Journal of the American Heart Association, 2022 Thromboinflammation has become a topic of key interest in cardiovascular disease and the prevention of diabetes complications because of the interplay between thrombosis and inflammation in diabetes.
Julia S Gauer +2 more
exaly +3 more sources
Platelets mediate fibrin-induced thromboinflammation and NETosis through a GPVI-polyphosphate-FXIIa procoagulant axis [PDF]
Blood Vessels, Thrombosis & Hemostasis: Fibrin deposits drive thromboinflammation and neutrophil extracellular trap (NET) formation (NETosis) in various pathophysiological situations, but the underlying mechanisms remain unclear.
Astride Perrot +10 more
doaj +2 more sources
Cytokine-Driven Hyperinflammation in Long COVID: Mechanisms, Biomarkers, Complement Dysregulation, and Emerging Immunotherapies-A Narrative Review. [PDF]
Health Sci RepABSTRACT Background and Aims Long COVID, also known as post‐acute sequelae of SARS‐CoV‐2 infection (PASC), is a multisystem condition characterized by persistent symptoms that continue beyond the acute phase of infection. Growing evidence indicates that sustained immune dysregulation involving cytokine‐mediated inflammation, complement activation ...
Obeagu EI.
europepmc +2 more sources
Essential Oils Modulating Inflammation, Oxidative Stress, Endothelial Dysfunction, and Thrombotic Pathways: Relevance to Thromboinflammation and Translational Perspectives [PDF]
BiomoleculesEssential oils (EOs) are complex plant-derived mixtures increasingly investigated for their anti-inflammatory, antioxidant, and vasoprotective properties.
Valeriu Mihai But +6 more
doaj +2 more sources
Thromboinflammation in dogs with virulent babesiosis [PDF]
Frontiers in Veterinary ScienceIntroductionBabesia rossi infection in dogs is associated with severe hemostatic dysregulation and systemic inflammation. The close interplay between innate immunity and coagulation in pathological states, including acute infections, may lead to thrombus
Amelia Goddard +5 more
doaj +2 more sources
The Role of CLEC-2 and Its Ligands in Thromboinflammation
Frontiers in Immunology, 2021 C-type lectin-like receptor 2 (CLEC-2, also known as CLEC-1b) is expressed on platelets, Kupffer cells and other immune cells, and binds to various ligands including the mucin-like protein podoplanin (PDPN).
Danyang Meng, Beibei Liu
exaly +3 more sources
ADAMTS13 as a thromboinflammatory brake at the vascular-immune interface: from viral immunothrombosis to the tumor microenvironment [PDF]
Frontiers in ImmunologyADAMTS13 is conventionally regarded as the protease whose severe deficiency causes thrombotic thrombocytopenic purpura (TTP). By cleaving shear-unfolded ultra-large and high-molecular-weight von Willebrand factor (VWF), ADAMTS13 limits a platelet- and ...
Peng Huang +3 more
doaj +2 more sources
Biomolecules, 2021 Interest in the role of coagulation and fibrinolysis in the nervous system was active in several laboratories dating back before cloning of the functional thrombin receptor in 1991. As one of those, our attention was initially on thrombin and plasminogen
Barry W Festoff, Chris Dockendorff
exaly +3 more sources
Risk factors and recurrent thrombosis in primary antiphospholipid syndrome
Exploration of Immunology, 2023 Aim: The study aims to evaluate the incidence of recurrent thromboses in patients with primary antiphospholipid syndrome (PAPS) and its association with the presence of different antiphospholipid antibodies (aPLs) and known thrombogenic risk factors ...
Fariza A. Cheldieva +6 more
doaj +1 more source
Thromboinflammation in oncogynecological patients
Акушерство, гинекология и репродукция, 2022 Studies of the pathogenesis of thrombosis and inflammation and their contribution to tumor progression and metastasis in cancer patients, initiated many decades ago, have been continued to this day.
E. V. Slukhanchuk +10 more
doaj +1 more source