Results 11 to 20 of about 3,493 (156)

Inhibition of SARS‐CoV‐2‐mediated thromboinflammation by CLEC2.Fc

EMBO Molecular Medicine, 2023
Thromboinflammation is the major cause of morbidity and mortality in COVID‐19 patients, and post‐mortem examination demonstrates the presence of platelet‐rich thrombi and microangiopathy in visceral organs.
Pei‐Shan Sung, Cheng‐Pu Sun, Mi‐Hua Tao, Shie‐Liang Hsieh   +3 more
doaj   +3 more sources

Coronavirus disease 2019 (COVID-19) and immune-mediated inflammatory rheumatic diseases: at the crossroads of thromboinflammation and autoimmunity [PDF]

Научно-практическая ревматология, 2020
Inflammation and coagulation are key basic mechanism of protection against all potentially pathogenic mechanical and biological factors targeting human organism from inner and outer environment.
E. L. Nasonov, T. V. Beketova, T. M. Reshetnyak, A. M. Lila, L. P. Ananieva, T. A. Lisitsyna, S. K. Soloviev   +6 more
doaj   +2 more sources

The Role of Thromboinflammation in Delayed Cerebral Ischemia after Subarachnoid Hemorrhage

Frontiers in Neurology, 2017
Delayed cerebral ischemia (DCI) is a major determinant of patient outcome following aneurysmal subarachnoid hemorrhage. Although the exact mechanisms leading to DCI are not fully known, inflammation, cerebral vasospasm, and microthrombi may all function ...
Devin W. McBride, Spiros L. Blackburn, Kumar T Peeyush, Kanako Matsumura, John H. Zhang, John H. Zhang   +5 more
doaj   +2 more sources

ACSL1 Aggravates Thromboinflammation by LPC/LPA Metabolic Axis in Hyperlipidemia Associated Myocardial Ischemia‐Reperfusion Injury

Advanced Science
Acute myocardial infarction (AMI) is associated with well‐established metabolic risk factors, especially hyperlipidemia and obesity. Myocardial ischemia‐reperfusion injury (mIRI) significantly offsets the therapeutic efficacy of revascularization ...
Shuai Jiang, Xueguang Lin, Bo Chen, Gang Chen, Kristine J.S. Kwan, Jing Liu, Qi Sun, Jie Wang, Yijie Lu, Jindong Tong, Ying Deng, Bo Yu, Jingdong Tang   +12 more
doaj   +2 more sources

Endothelial cell activation enhances thromboinflammation in vaccine-induced immune thrombotic thrombocytopenia

Blood Advances
: Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare but serious complication of the ChAdOx1 nCOV-19 vaccine. In Australia, the diagnosis of VITT required the detection of antibodies against platelet factor 4 (PF4) in plasma using a PF4 ...
Alexander Dupuy, Xiaoming Liu, Yvonne Kong, Miao Qi, Jose Perdomo, Jemma Fenwick, Jessica Tieng, Bede Johnston, Qiyu Sara Shi, Mark Larance, Yingqi Zhang, Lining Arnold Ju, Paul Coleman, Jennifer Gamble, Elizabeth E. Gardiner, Mortimer Poncz, Huyen Tran, Vivien Chen, Freda H. Passam   +18 more
doaj   +2 more sources

Low-Molecular-Weight Fucoidan Inhibits Thromboinflammation and Ameliorates Deep Vein Thrombosis via Targeting S100A8/A9

Marine Drugs
Deep vein thrombosis (DVT) is a prevalent life-threatening complication among hospitalized patients. DVT is characterized by the hypercoagulability and thromboinflammation in which platelet activation and neutrophil extracellular trap (NET) formation are
Yiting Feng, Weiqing Zhao, Siwen Fang, Jingwen Zhao, Wanshuai Wang, Shaoyun Zhou, Tianyu Wang, Xinke Fang, Xue Chen, Muhammad Awais, Chao Cai, Chuanbin Shen, Ming Liu   +12 more
doaj   +2 more sources

Venous Air Embolism Activates Complement C3 Without Corresponding C5 Activation and Trigger Thromboinflammation in Pigs [PDF]

, 2022
Introduction: Air embolism may complicate invasive medical procedures. Bubbles trigger complement C3-mediated cytokine release, coagulation, and platelet activation in vitro in human whole blood.
Nilsen, Bent Aksel, Ludviksen, Judith K, Christiansen, Dorte, Landsem, Anne, Mollnes, Tom Eirik, Fure, Hilde, Dybwik, Knut Gustav, Storm, Benjamin, Braaten, Tonje, Nielsen, Erik Waage, Pettersen, Kristin   +10 more
core   +3 more sources

Editorial: Platelets and Immune Responses During Thromboinflammation [PDF]

, 2020
The word thromboinflammation appeared in 2004 to describe the interactions and cooperation between platelets and neutrophils in the context of arterial in-stent restenosis (1).
Negrotto, Soledad, Jenne, Craig N., Schattner, Mirta Ana, Ho-Tin-Noe, Benoit   +3 more
core   +1 more source

Case Report: Co-occurrence of Myocarditis and Thrombotic Microangiopathy Limited to the Heart in a COVID-19 Patient

Frontiers in Cardiovascular Medicine, 2021
We report on an impressive case of a previously healthy 47-year-old female Caucasian SARS-CoV-2 positive patient who died within 48 h after initial cardiac symptoms.
Thomas Menter, Nadine Cueni, Eva Caroline Gebhard, Alexandar Tzankov   +3 more
doaj   +1 more source

Thromboinflammatory response is increased in pancreas transplant alone versus simultaneous pancreas-kidney transplantation and early pancreas graft thrombosis is associated with complement activation

Frontiers in Immunology, 2023
BackgroundPancreas transplant alone (PTA) recipients are more affected by pancreas graft thrombosis, and graft loss compared to simultaneous pancreas-kidney (SPK) recipients.
Kristina Rydenfelt, Kristina Rydenfelt, Kristina Rydenfelt, Gisle Kjøsen, Gisle Kjøsen, Rune Horneland, Judith Krey Ludviksen, Trond Geir Jenssen, Trond Geir Jenssen, Pål-Dag Line, Pål-Dag Line, Tor Inge Tønnessen, Tor Inge Tønnessen, Tom Eirik Mollnes, Tom Eirik Mollnes, Tom Eirik Mollnes, Håkon Haugaa, Håkon Haugaa, Håkon Haugaa, Søren Erik Pischke, Søren Erik Pischke, Søren Erik Pischke   +21 more
doaj   +1 more source