Results 101 to 110 of about 19,945 (215)

Challenges of obtaining cultured corneal endothelial cells for regenerative purposes

Вестник трансплантологии и искусственных органов
Human posterior corneal epithelium (corneal endothelium) has limited proliferative activity both in vivo and in vitro. Disease or dysfunction in these cells leads to impaired corneal transparency of varying degrees of severity, up to blindness. Currently,
D. S. Ostrovski, S. A. Borzenok, B. E. Malyugin, O. P. Antonova, M. Kh. Khubetsova, T. Z. Kerimov   +5 more
doaj   +1 more source

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

MedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi, Shahin Ramazi, Mona Darvazi, Sepideh Yoosefi, Melika Abbasi, Shirin Farsad   +5 more
wiley   +1 more source

Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment

MedComm, Volume 7, Issue 4, April 2026.
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai, Chongxiang Wang, Ping Jiang, Xiaopeng Mei   +3 more
wiley   +1 more source

Tumor‐Bearing Status Accelerates Bleomycin‐Induced Pulmonary Inflammation via Endothelial Activation

Thoracic Cancer, Volume 17, Issue 7, April 2026.
In subcutaneous tumor‐bearing mice, inflammatory cell infiltration into the lung was aggravated via endothelial activation. The tumor‐bearing status additively aggravated BLM‐induced lung inflammation. Proinflammatory changes in the lungs accelerated by tumor‐bearing status might be involved in the development of drug‐induced lung inflammation ...
Shoko Isoyama, Kakuhiro Yamaguchi, Hiroshi Iwamoto, Yasushi Horimasu, Kunihiko Funaishi, Kiyofumi Shimoji, Shinjiro Sakamoto, Takeshi Masuda, Taku Nakashima, Shinichiro Ohshimo, Hironobu Hamada, Noboru Hattori   +11 more
wiley   +1 more source

Overproduction of 42 Amino Acids Long Amyloid Beta Leads to Activation of Secretory Autophagy and Development of Drusen‐Like Structures Originating From Retinal Pigment Epithelium

The FASEB Journal, Volume 40, Issue 5, 15 March 2026.
The role of 42 amino acids long amyloid beta (Aβ) in the retinal pigment epithelium (RPE) was investigated using 5xFAD mice model overproducing Aβ. The RPE cells of 5xFAD mice showed increased oxidative stress, accumulation of autophagy‐destined proteins, increased expression of secretory autophagy markers, and increase in epithelial‐to‐mesenchymal ...
Johanna Ruuth, Toni Tamminen, Elisa Toropainen, Heikki Tanila, Juha M. T. Hyttinen, Tarja Malm, Kai Kaarniranta, Ali Koskela   +7 more
wiley   +1 more source

Storage of Corneas With Predissected Descemet Membrane in an Active Storage Machine. [PDF]

Transl Vis Sci Technol
Goin P, Poinard S, Dorado O, Perrache C, He Z, Ninotta S, Gain P, Gauthier AS, Thuret G.   +8 more
europepmc   +1 more source

Peters Anomaly in a Miniature Schnauzer Documented by Spectral-Domain Optical Coherence Tomography: A Case Report. [PDF]

Clin Case Rep
Miwa Y, Lee D, Inukai Y.
europepmc   +1 more source

Femto-DSAEK for deep posterior stromal opacity: a lamellar alternative to PK in failed DMEK. [PDF]

Am J Ophthalmol Case Rep
Lucchino L, Romano D, Vaccaro S, Moramarco A, Semeraro F, Fontana L, Romano V.   +6 more
europepmc   +1 more source

Early Transcriptomic and Pathologic Changes of Col8a2 Mutant Fuchs Endothelial Corneal Dystrophy. [PDF]

Invest Ophthalmol Vis Sci
Zhao X, Duan H, Dou S, Li X, Lin Y, Zhao C, Li D, Zhou L, Li Z, Zhou Q.   +9 more
europepmc   +1 more source

Visualization of Ex Vivo Porcine Corneal Endothelial Cells Using Smartphone-Assisted Specular Reflection With Slit-Lamp Biomicroscopy. [PDF]

Vet Ophthalmol
Kim Y, Kang S, Seo K.
europepmc   +1 more source