Results 101 to 110 of about 36,948 (267)

Transcriptomic Analysis of Cultured Corneal Endothelial Cells as a Validation for Their Use in Cell Replacement Therapy

Cell Transplantation, 2016
The corneal endothelium plays a primary role in maintaining corneal homeostasis and clarity and must be surgically replaced with allogenic donor corneal endothelium in the event of visually significant dysfunction.
Ricardo F. Frausto, Derek J. Le, Anthony J. Aldave M.D.   +2 more
doaj   +1 more source

Congenital aniridia: European COST action ANIRIDIA‐NET guidelines for diagnosis, management and care

Acta Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare ocular disorder affecting the majority of eye structures and can be associated with systemic manifestations. The main visible phenotypic characteristic is the partial or complete absence of the iris; however, foveal hypoplasia is a more frequent and reliable clinical sign. Other ocular comorbidities are associated
Davide Romano, Vito Romano, Alejandra Daruich, Giulio Ferrari, Matthieu Robert, Francesco Semeraro, Neil Lagali, Dominique Bremond‐Gignac, the ANIRIDIA‐NET Clinical Guidelines Working Group, Miriam Barbany, Claus Cursiefen, Stefano Ferrari, Francisco Figueiredo, Christina Grupcheva, Jesper Hjortdal, Elke Kreps, Erlend Landsend, Laura Mauring, Hilde Pedersen, Nora Szentmáry, Bogumil Wowra, the Aniridia‐Europa and Geniris Working Group, Sophie Valleix, Juan Álvarez de Toledo, James Lauderdale, Tor Paaske Utheim, Paolo Rama   +26 more
wiley   +1 more source

Effects of atracurium besylate on corneal endothelium of chickens: in vitro study

Pesquisa Veterinária Brasileira
: The aim of this study was to investigate the acute effects of atracurium besylate on cellular damage in corneal endothelium of chickens. Twenty healthy chicken eyes were assigned to the following groups: Group 1 (G1), experimental group (n=10); and ...
Celeste B. Guimarães, Luciane Albuquerque, Marcela Torikachvili, Eduarda V. Vargas, Cecilia C. Dall’Agnol, Tanise C. Silva, João A.T. Pigatto   +6 more
doaj   +1 more source

Dual control of vascular tone and remodelling by ATP released from nerves and endothelial cells [PDF]

, 2008
Purinergic signalling is important both in short-term control of vascular tone and in longer-term control of cell proliferation, migration and death involved in vascular remodelling.
Burnstock, G
core  

Comparison of preservation and transportation protocols for preloaded Descemet membrane endothelial keratoplasty [PDF]

, 2017
BACKGROUND/AIMS: Descemet membrane endothelial keratoplasty (DMEK) preparation is technically demanding and is a limiting factor for uptake of this kind of surgery.
Ferrari, Stefano, Kaye, Stephen B, Levis, Hannah J, Parekh, Mohit, Ponzin, Diego, Romano, Vito, Ruzza, Alessandro, Willoughby, Colin E   +7 more
core   +2 more sources

Exploring the histopathological signature of repeat‐mediated Fuchs endothelial corneal dystrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the histological differences between Fuchs endothelial corneal dystrophy (FECD) cases with and without the most common genetic risk factor, expansion of a CTG repeat (CTG18.1) within the TCF4 gene. Methods Formalin‐fixed paraffin‐embedded corneal tissues were compared retrospectively, and CTG18.1 status was determined from
Anne‐Marie S. Kladny, Nihar Bhattacharyya, Marcos Abreu Costa, Stephen J. Tuft, Caroline Thaung, Alice E. Davidson   +5 more
wiley   +1 more source

Refractive change following pseudophakic vitrectomy: a retrospective review [PDF]

, 2008
Background To assess the occurrence and magnitude of refractive change in pseudophakic eyes undergoing 20 gauge pars plana vitrectomy without scleral buckling and to investigate possible aetiological factors.
Anthony Hildreth, CY Hu, David HW Steel, James Ng, JB Randleman, Jean-Pierre Danjoux, JR McEwan, JW Jeoung, L Zheng, M Shioya, O Cekic, O Findl, P Brazitikos, RV Campo, S Cisiecki, Sinead Byrne, T Eckert, T Oshika, Y Suzuki, YR Sharma   +19 more
core   +5 more sources

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

Acta Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry, S. Suiwal, M. Amini, F. N. Fries, A. Náray, L. Latta, Z. Li, S. Li, S. Liu, S. L. Hsu, S. Kundu, G. Tóth, S. Trusen, J. Zimmermann, B. Seitz, B. Käsmann‐Kellner, Z. Hoxha, A. Langenbucher, O. Stachs, M. Cortón‐Perez, K. Tory, A. Csorba, Z. Z. Nagy, M. C. Acosta, J. Gallar, M. Csidey, E. Maka, T. Stachon   +27 more
wiley   +1 more source

Human Fetal Keratocytes Have Multipotent Characteristics in the Developing Avian Embryo [PDF]

, 2013
The human cornea contains stem cells that can be induced to express markers consistent with multipotency in cell culture; however, there have been no studies demonstrating that human corneal keratocytes are multipotent.
Bronner, Marianne E., Chao, Jennifer R., Lwigale, Peter Y.   +2 more
core   +1 more source

Industry‐Reported Financial Relationships Among American Ophthalmology Society Board Members

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To assess financial disclosures of American ophthalmology society board members by comparing self‐reported disclosures with industry‐reported payments and examining characteristics linked to larger financial relationships. Methods In this retrospective, cross‐sectional study, we assessed all governance board members from American ...
Mostafa Bondok, Leonardo Lando, Anne Xuan‐Lan Nguyen, Michael Knafo, Albert Y. Wu   +4 more
wiley   +1 more source