Results 101 to 110 of about 266,603 (335)
Epigenetics and immunometabolism in diabetes and aging [PDF]
, 2018 Significance: A strong relationship between hyperglycemia, impaired insulin pathway and cardiovascular disease in type 2 diabetes (T2D) is linked to oxidative stress and inflammation.
Cosentino, Francesco, Guzik, Tomasz J.
core +5 more sources
Lymphatic vascularisation and involvement of Lyve-1+ macrophages in the human onchocerca nodule. [PDF]
PLoS ONE, 2009 Onchocerciasis, caused by the filarial nematode Onchocerca volvulus, is a parasitic disease leading to debilitating skin disease and blindness, with major economic and social consequences. The pathology of onchocerciasis is principally considered to be a
Tarik Attout +12 more
doaj +1 more source
The lymphatic vasculature in lung function and respiratory disease
Frontiers in Medicine, 2023 The lymphatic vasculature maintains tissue homeostasis via fluid drainage in the form of lymph and immune surveillance due to migration of leukocytes through the lymphatics to the draining lymph nodes.
Anjali Trivedi +2 more
doaj +1 more source
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
Chemokine Signaling Directs Trunk Lymphatic Network Formation along the Preexisting Blood Vasculature [PDF]
, 2012 SummaryThe lymphatic system is crucial for fluid homeostasis, immune responses, and numerous pathological processes. However, the molecular mechanisms responsible for establishing the anatomical form of the lymphatic vascular network remain largely ...
Butler, Matthew +6 more
core +1 more source
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
Mechanisms of organogenesis of primary lymphoid follicles [PDF]
arXiv, 2006 Primary lymphoid follicles in secondary lymphoid tissue of mammals are the backbone for the formation of follicular dendritic cell networks. These are important for germinal center reactions. In the context of organogenesis molecular requirements for the formation of follicles have been identified.
arxiv
Pump efficacy in a fluid-structure interaction model of a chain of contracting lymphangions [PDF]
arXiv, 2020 The transport of lymph through the lymphatic vasculature is the mechanism for returning excess interstitial fluid to the circulatory system, and it is essential for fluid homeostasis. Collecting lymphatic vessels comprise a significant portion of the lymphatic vasculature and are divided by valves into contractile segments known as lymphangions ...
arxiv
Uncertainty quantification of a three-dimensional in-stent restenosis model with surrogate modelling [PDF]
arXiv, 2021 In-Stent Restenosis is a recurrence of coronary artery narrowing due to vascular injury caused by balloon dilation and stent placement. It may lead to the relapse of angina symptoms or to an acute coronary syndrome. An uncertainty quantification of a model for In-Stent Restenosis with four uncertain parameters (endothelium regeneration time, the ...
arxiv
Lymphatic Programing and Specialization in Hybrid Vessels
Frontiers in Physiology, 2020 Building on a large body of existing blood vascular research, advances in lymphatic research have helped kindle broader investigations into vascular diversity and endothelial plasticity.
John B. Pawlak, Kathleen M. Caron
doaj +1 more source