The Lymphatic Endothelium in the Context of Radioimmuno-Oncology
Cancers, 2022 The study of lymphatic tumor vasculature has been gaining interest in the context of cancer immunotherapy. These vessels constitute conduits for immune cells’ transit toward the lymph nodes, and they endow tumors with routes to metastasize to the lymph nodes and, from them, toward distant sites.
Lucía Suárez +2 more
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Slit2/Robo4 signaling modulates HIV-1 gp120-induced lymphatic hyperpermeability. [PDF]
PLoS Pathogens, 2012 Dissemination of HIV in the host involves transit of the virus and virus-infected cells across the lymphatic endothelium. HIV may alter lymphatic endothelial permeability to foster dissemination, but the mechanism is largely unexplored.
Xuefeng Zhang +5 more
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The Lymphatic Headmaster of the Mast Cell-Related Splanchnic Inflammation in Portal Hypertension
Cells, 2019 Portal hypertension is a common complication of liver disease, either acute or chronic. Consequently, in chronic liver disease, such as the hypertensive mesenteric venous pathology, the coexisting inflammatory response is classically characterized by the
Maria-Angeles Aller +4 more
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Pulmonary lymphatic function and its research progress in pulmonary diseases
生物医学转化, 2023 The lymphatic system is a unidirectional network in which lymph fluid flows centripetally along a series of lymphatic channels and eventually into the veins, so the lymphatic system can also be considered an auxiliary part of the venous system and an ...
Kang Xuya +4 more
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Сибирский научный медицинский журнал, 2019 The aim of this work was a comparative study of the ultrastructural organization of lymphatic structures in the choroid and conjunctiva of the human eye. Material and methods.
S. R. Nogovitsina +5 more
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Aquaporin-4 Functionality and Virchow-Robin Space Water Dynamics: Physiological Model for Neurovascular Coupling and Glymphatic Flow. [PDF]
, 2017 The unique properties of brain capillary endothelium, critical in maintaining the blood-brain barrier (BBB) and restricting water permeability across the BBB, have important consequences on fluid hydrodynamics inside the BBB hereto inadequately ...
Igarashi, Hironaka +3 more
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Initial afferent lymphatic vessels controlling outbound leukocyte traffic from skin to lymph nodes.
Frontiers in Immunology, 2013 Tissue drains fluid and macromolecules through lymphatic vessels, which are lined by a specialized endothelium that expresses peculiar differentiation proteins, not found in blood vessels (i.e: LYVE-1, Podoplanin, PROX-1 and VEGFR-3).
Ignacio eMelero +2 more
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KSHV Induction of Angiogenic and Lymphangiogenic Phenotypes
Frontiers in Microbiology, 2012 Kaposi’s Sarcoma is a highly vascularized tumor supporting large amounts of neo-angiogenesis. The major cell type in KS tumors is the spindle cell, a cell that expresses markers of lymphatic endothelium. KSHV, the etiologic agent of KS, is found in the
Terri A. DiMiao, Michael eLagunoff
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PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration
Nature Communications, 2022 The Programmed death-1 (PD-1) and its ligand PD-L1 are critical checkpoints in the regulation of immune responses. Here the authors implicate PD-L1 signalling at lymphatic endothelium in the regulation of transendothelial migration of T cells.
Wenji Piao +14 more
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Colon cancer cell-derived 12(S)-HETE induces the retraction of cancer-associated fibroblast via MLC2, RHO/ROCK and Ca2+ signalling [PDF]
, 2016 Retraction of mesenchymal stromal cells supports the invasion of colorectal cancer cells (CRC) into the adjacent compartment. CRC-secreted 12(S)-HETE enhances the retraction of cancer-associated fibroblasts (CAFs) and therefore, 12(S)-HETE may enforce ...
Bago-Horvath, Zsuzsanna +22 more
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