The vascular endothelium [PDF]
Over the last 40 years, research on the vascular endothelium has provided important clues for the understanding of vascular disease. This new knowledge is finding its way into clinical medicine.
Salvador Moncada
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Contributions of the Endothelium to Vascular Calcification [PDF]
Vascular calcification (VC) increases morbidity and mortality and constitutes a significant obstacle during percutaneous interventions and surgeries. On a cellular and molecular level, VC is a highly regulated process that involves abnormal cell transitions and osteogenic differentiation, re-purposing of signaling pathways normally used in bone, and ...
Li Zhang +5 more
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Morphological Study on Development of Vascular Endothelium in Chick Embryo [PDF]
The vascular endothelium and hematopoietic stem cells are believed to derive from common progenitor cells called hemangioblasts. However, morphological study on the development of vascular endothelial cell has been scarce.
Yaiko Hara
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Intraluminal application of vascular endothelial growth factor enhances healing of microvascular anastomosis in a rat model [PDF]
Background: Early reconstitution after injury to the endothelium is an important feature for reducing a number of vessel wall pathologies. We investigated the effect of vascular endothelial growth factor ( VEGF) and its impact on the vascular remodeling ...
Hollenberg, S. M. +8 more
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Moderate Champagne consumption promotes an acute improvement in acute endothelial-independent vascular function in healthy human volunteers [PDF]
Epidemiological studies have suggested an inverse correlation between red wine consumption and the incidence of CVD. However, Champagne wine has not been fully investigated for its cardioprotective potential. In order to assess whether acute and moderate
David Vauzour +42 more
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Cross-Talk of NADPH Oxidases and Inflammation in Obesity
Obesity is a major risk factor for cardiovascular and metabolic diseases. Multiple experimental and clinical studies have shown increased oxidative stress and inflammation linked to obesity.
Henning Morawietz +6 more
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The regulation of function of endothelial cell–cell junctions is fundamental in sustaining vascular integrity. The polycistronic microRNA (miR) complexes containing miR-23a-27a-24-2, and 23b-27b-24-1 are predicted to target the majority of major ...
Jia Li +6 more
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Interaction between maternal and offspring diet to impair vascular function and oxidative balance in high fat fed male mice [PDF]
Aims: to determine the impact of maternal and post-weaning consumption of a high fat diet on endothelium-dependent vasorelaxation and redox regulation in adult male mouse offspring.Methods: female C57BL6J mice were fed an obesogenic high fat diet (HF, 45%
Geraldine F Clough +41 more
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Vascular endothelium in diabetes [PDF]
Three decades ago a revolutionary idea was born that ascribed to dysfunctional endothelia some manifestations of diabetes, the Steno hypothesis, so named after the Steno Diabetes Center, Gentofte, in Denmark. Here I briefly outline the accomplishments accrued in the past 15 years to buttress this hypothesis.
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Effects of prior moderate exercise on postprandial metabolism and vascular function in lean and centrally obese men [PDF]
Objectives: We investigated whether a session of prior exercise could ameliorate postprandial endothelial dysfunction. Background: Endothelial function is impaired after fat ingestion, and this may be related to rises in triglyceride concentrations.
John R. Petrie +24 more
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