Glu298Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function [PDF]
An endothelial nitric oxide synthase (eNOS) gene polymorphism (Glu298Asp) has been associated with cardiovascular disease. We investigated whether carriage of the polymorphism was associated with functional changes in the endothelium, and how genotype ...
Jeerooburkhan, N. +20 more
core +1 more source
.: Endothelium regulates vascular tone via release of endothelium-derived relaxing factors (EDRF) including nitric oxide (NO), prostaglandin I2 (PGI2), and endothelium-derived hyperpolarizing factor (EDHF).
Xin Jin +6 more
doaj +1 more source
Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]
The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Erl, Wolfgang +7 more
core +1 more source
Endothelium-Derived Relaxing Factor–Mediated Vasodilation in Mouse Mesenteric Vascular Beds
The endothelium in rat mesenteric vascular beds has been demonstrated to regulate vascular tone by releasing mainly endothelium-derived hyperpolarizing factor (EDHF), which is involved in the activation of K+ channels and gap-junctions.
Hiroki Fujiwara +7 more
doaj +1 more source
Organ-Specific Endothelial Dysfunction Following Total Body Irradiation Exposure
As the single cell lining of the heart and all blood vessels, the vascular endothelium serves a critical role in maintaining homeostasis via control of vascular tone, immune cell recruitment, and macromolecular transit.
Guru Prasad Sharma, Heather A. Himburg
doaj +1 more source
Involvement of endothelium-derived relaxing factor in the pressure control of renin secretion from isolated perfused kidney [PDF]
Using isolated rat kidneys perfused at controlled pressure, we examined a potential role of endothelium-derived relaxing factor (EDRF) in the pressure control of renin secretion.
Kurtz, Armin +5 more
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Contribution of Oxidative Stress to Endothelial Dysfunction in Hypertension
Endothelial dysfunction is the hallmark of hypertension, which is a multifactorial disorder. In the cardiovascular system reactive oxygen species play a pivotal role in controlling the endothelial function and vascular tone.
Bruno Rodrigues Silva +2 more
doaj +1 more source
PECAM-1 engagement counteracts ICAM-1-induced signaling in brain vascular endothelial cells [PDF]
Interactions between leukocytes and vascular endothelial cells are mediated by a complex set of membrane adhesion molecules which transduce bi-directional signals in both cell types.
Laran-Chich, M.-P. +13 more
core +1 more source
Regeneration of the Endothelium in Vascular Injury [PDF]
The endothelium mediates relaxations (dilatations) of the underlying vascular smooth muscle cells. The endothelium-dependent relaxations are due to the release of non-prostanoid vasodilator substances. The best characterized endothelium-derived relaxing factor (EDRF) is nitric oxide (NO).
openaire +4 more sources
Endothelium-dependent and -independent aortic vascular relaxation in SED and EX mice. [PDF]
A. Phenylephrine (PE)-mediated vascular contraction in aortic rings from SED and EX mice was expressed as a percentage maximum response to KPSS (n = 8 per group). B.
Peter F. Bodary (4173751) +3 more
core +1 more source

