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Vascular Endothelium and Blood Flow
2006Major advances have been made over the last decade towards the elucidation of the molecular mechanisms involved in the endothelium-dependent regulation of vascular tone and blood flow. While the primary endothelium-derived vasodilator autacoid is nitric oxide, it is clear that epoxyeicosatrienoic acids and other endothelium-derived hyperpolarising ...
Ingrid Fleming, Rudi Busse
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Hypoxia and the vascular endothelium
Fibrinolysis and Proteolysis, 1997Summary The vascular endothelium responds to a decrease in extracellular oxygen by expressing a specific set of proteins. At present, we know that this response can be erythropoietic, angiogenic and glycolytic. The cellular response to hypoxia has important implications for the medical management of cardiovascular and myocardial ischemia.
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The endothelium: vascular control of haemostasis
European Journal of Obstetrics & Gynecology and Reproductive Biology, 2001Within many general functions the endothelium is equipped with a number of mechanisms that prevent thrombus formation in the circulatory system. It harbours factors that interrupt the coagulation cascade, such as antithrombin III, the protein C receptor thrombomodulin, and tissue factor pathway inhibitor.
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Antigenic Heterogeneity of Vascular Endothelium
1991The antigenic status of vascular endothelium from different sites of the normal adult and fetal human cardiovascular system was investigated. Tissues included aorta (n = 9), pulmonary artery (n = 8), coronary artery (n = 6), ventricle/atrium (n = greater than 10), lymph node (n = 2), fetal whole heart (n = 3), and umbilical cord (n = 7).
Christopher Page+3 more
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Vascular Dynamics and the Endothelium
1986As the heart rhythmically beats and ejects its periodic output, there are a wide range of phenomena that take place as the pressure pulse propagates through the vascular system. Initially, the interest in vascular dynamics was simply on this phenomenon of wave propagation, and workers such as Young, Frank, Moens, and Korteweg are associated with this ...
M. Sato, M. J. Levesque, R. M. Nerem
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Immunobiology of human vascular endothelium
Immunologic Research, 1999The author's laboratory studies interactions between human T lymphocytes and vascular endothelial cells (EC). Our work is organized around three hypotheses. First, we propose that vascular EC can initiate secondary (i.e., recall) immune reactions by presenting antigenic peptide-major histocompatibility complex (MHC) complexes to those circulating ...
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Vascular Endothelium and Hypovolemic Shock
Current Vascular Pharmacology, 2016Endothelium is a site of metabolic activity and has a major reservoir of multipotent stem cells. It plays a vital role in the vascular physiological, pathophysiological and reparative processes. Endothelial functions are significantly altered following hypovolemic shock due to ischemia of the endothelial cells and by reperfusion due to resuscitation ...
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Vascular endothelium, haemostasis and thrombosis
Blood Reviews, 1988The vascular endothelium consists of a monolayer of cells. Integrity of the endothelium is essential for maintenance of blood fluidity as the subendothelium is composed of structures which rapidly activate platelets and coagulation. Recent research indicates that the endothelium is involved in other processes particularly vasoactivity, immune reactions
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Endothelium and vascular reactivity
Journal of Molecular and Cellular Cardiology, 1985J.A. Angus, T.M. Cocks
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