Results 211 to 220 of about 711,120 (258)
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Epigenetics of the vascular endothelium
Journal of Applied Physiology, 2010Classical models of transcription in vascular endothelial cells, specifically the cis/trans paradigm, have limitations. For instance, how does the environment have chronic effects on gene expression in endothelial cells after weeks or years? When an endothelial cell divides, how is this information transmitted to daughter cells?
Matthew Shu-Ching, Yan +2 more
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Hemodynamics and the Vascular Endothelium
Journal of Biomechanical Engineering, 1993The endothelium, once thought to be a passive, non-thrombogenic barrier, is now recognized as being a dynamic participant in vascular biology and pathobiology. Part of its dynamic nature is due to the influence of the mechanical environment imposed by the hemodynamics of the vascular system.
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Eicosanoids and the Vascular Endothelium
2006Cyclooxygenase (COX) enzymes catalyse the biotransformation of arachidonic acid to prostaglandins which subserve important functions in cardiovascular homeostasis. Prostacyclin (PGI2) and prostaglandin (PG)E2, dominant products of COX activityin macro- and microvascular endothelial cells, respectively, in vitro, modulate the interaction of blood cells ...
K, Egan, G A, FitzGerald
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The Vascular Endothelium in Hypertension
2006The vascular endothelium plays a fundamental role in the basal and dynamic regulation of the circulation. Thus, it has a crucial role in the pathogenesis of hypertension. A spectrum of vasoactive substances is synthesised in the endothelium; of these, nitric oxide (NO), prostacyclin (PGI2) and endothelin (ET)-1 are the most important.
L E, Spieker +2 more
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ION CHANNELS IN VASCULAR ENDOTHELIUM
Annual Review of Physiology, 1997▪ Abstract The functional impact of ion channels in vascular endothelial cells (ECs) is still a matter of controversy. This review describes different types of ion channels in ECs and their role in electrogenesis, Ca2+ signaling, vessel permeability, cell-cell communication, mechano-sensor functions, and pH and volume regulation.
Nilius, Bernd +2 more
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The Vascular Endothelium in Scleroderma
International Reviews of Immunology, 1995(1995). The Vascular Endothelium in Scleroderma. International Reviews of Immunology: Vol. 12, No. 2-4, pp. 227-245.
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Vascular Endothelium and Atherosclerosis
2006Atherosclerosis depends critically on altered behavior of the intrinsic cells of the artery wall, the endothelial cells and smooth muscle cells, and inflammatory leukocytes that join them in the arterial intima during the atherogenic process. The homeostatic properties of the normal endothelium contribute importantly to maintenance of aspects of ...
P, Libby, M, Aikawa, M K, Jain
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Vascular endothelium in cancer
Cell and Tissue Research, 2008The vascular endothelium plays an essential role during organogenesis and in tissue homeostasis. Growing evidence also supports its essential and complex role in tumour biology and cancer progression. In particular, excessive proliferation and transformation or dysfunction of endothelial cells leads to pathological (lymph)angiogenesis or vascular ...
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British journal of hospital medicine, 1993
Endothelium lines all blood vessels and the cardiac cavities and has a central role in cardiovascular homeostasis. It releases several potent substances which mediate the control of vascular tone and cardiac contraction. Endothelial dysfunction is implicated in many disease states.
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Endothelium lines all blood vessels and the cardiac cavities and has a central role in cardiovascular homeostasis. It releases several potent substances which mediate the control of vascular tone and cardiac contraction. Endothelial dysfunction is implicated in many disease states.
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Nitric Oxide and the Vascular Endothelium
2006The vascular endothelium synthesises the vasodilator and anti-aggregatory mediator nitric oxide (NO) from L-arginine. This action is catalysed by the action of NO synthases, of which two forms are present in the endothelium. Endothelial (e)NOS is highly regulated, constitutively active and generates NO in response to shear stress and other ...
Moncada, S., Higgs, E. A.
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