Results 61 to 70 of about 231,849 (311)

VASOMOTOR FUNCTION OF THE ENDOTHELIUM IN PATIENTS WITH CHRONIC KIDNEY DISEASE AND HYPERTENSION

open access: yesУкраїнський Журнал Нефрології та Діалізу, 2017
Investigation of the functional state of the vascular endothelium contributes to the further study of the mechanisms of development and pharmacological correction, particularly in hypertensive patients with chronic kidney disease.
N. V. Demikhova   +3 more
doaj   +1 more source

Investigation of Trypanosoma-induced vascular damage sheds insights into Trypanosoma vivax sequestration

open access: yesThe Cell Surface, 2023
Multiple blood-borne pathogens infecting mammals establish close interactions with the host vascular endothelium as part of their life cycles. In this work, we investigate differences in the interactions of three Trypanosoma species: T.
Sara Silva Pereira   +4 more
doaj   +1 more source

The Vascular Endothelium and Human Diseases [PDF]

open access: yesInternational Journal of Biological Sciences, 2013
Alterations of endothelial cells and the vasculature play a central role in the pathogenesis of a broad spectrum of the most dreadful of human diseases, as endothelial cells have the key function of participating in the maintenance of patent and functional capillaries.
Rajendran, Peramaiyan   +6 more
openaire   +2 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Kaposin-B enhances the PROX1 mRNA stability during lymphatic reprogramming of vascular endothelial cells by Kaposi's sarcoma herpes virus. [PDF]

open access: yes, 2010
Kaposi's sarcoma (KS) is the most common cancer among HIV-positive patients. Histogenetic origin of KS has long been elusive due to a mixed expression of both blood and lymphatic endothelial markers in KS tumor cells.
Kafka, Darren   +37 more
core   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Efeito do extrato aquoso de erva-mate (llex paraguariensis) na reatividade vascular: enfoque na aterosclerose experimental [PDF]

open access: yes, 2005
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em FarmáciaA disfunção endotelial e o envolvimento de radicais livres exercem um importante papel na patogênese da aterosclerose.
Felippi, Regina
core  

Step-wise CAG@PLys@PDA-Cu2+ modification on micropatterned nanofibers for programmed endothelial healing

open access: yesBioactive Materials, 2023
Native-like endothelium regeneration is a prerequisite for material-guided small-diameter vascular regeneration. In this study, a novel strategy is proposed to achieve phase-adjusted endothelial healing by step-wise modification of parallel-microgroove ...
Bingcheng Yi   +5 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Understanding Vascular Endothelium [PDF]

open access: yes, 2014
Understanding Vascular Endothelium : Nature’s Container for Blood The entire cardiovascular system, from the chambers of the heart to the smallest capillaries of peripheral tissues, is lined by a single-cell-thick continuous layer—the vascular ...
Gimbrone, Michael A.
core   +1 more source

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