Rethinking Fluid Resuscitation in Septic Shock: A Phase-Adapted, Endothelium-Sparing Approach to Mitigate Capillary Leak. [PDF]
J Inflamm ResLi B, Zhao L.
europepmc +1 more source
Assembly of Cell‐Seeded 3D Printed Hydrogel Modules with Perfusable Channel Networks
Advanced Functional Materials, EarlyView.Macroscale assembly was utilized to prepare perfusable tissue constructs from individually 3D printed hydrogel modules with embedded branched channel networks and port arrays for cell seeding. Novel multi‐material bioreactors were fabricated to facilitate the gluing of individual modules and the perfusion culture of assembled modular constructs seeded ...
Zachary J. Geffert +10 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng +16 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
Editorial: Where Is Waldo: Contextualizing the Endothelial Cell in the Era of Precision Biology
Frontiers in Cardiovascular Medicine, 2020 Zorina S. Galis
doaj +1 more source
Ultrastructural Analysis of the Saphenous Vein Endothelium in a Patient With Proinflammatory Comorbidities Undergoing Coronary Artery Bypass Grafting. [PDF]
Case Rep MedDuarte Pimentel M +2 more
europepmc +1 more source
Further analysis of the predictability of corneal endothelial cell density estimates when polymegethism is present [PDF]
, 2017 Doughty, Michael J.
core +1 more source
Advanced Healthcare Materials, EarlyView.Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo +6 more
wiley +1 more source
Endothelial Cells as Active Lipid Gatekeepers: Vascular Control of Lipid Handling and Metabolic Homeostasis. [PDF]
NutrientsKanda T, Urai H.
europepmc +1 more source
Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling
Advanced Healthcare Materials, EarlyView.Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee +7 more
wiley +1 more source