Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab +8 more
wiley +1 more source
Advanced Materials for Biologics Delivery to Brain Tumors
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
Evaluation of an Adapted Murine Electrolytic Model of Venous Injury in Wistar Rats: Histopathological Characterization and Challenges in Model Adaptation. [PDF]
Murariu-Gligor EE +5 more
europepmc +1 more source
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol +16 more
wiley +1 more source
An Optimized Mechanical Peeling Protocol for Mouse Corneal Endothelium. [PDF]
Song Z, Song L, Mei H.
europepmc +1 more source
Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo +9 more
wiley +1 more source
Medulloblastoma Spatial Transcriptomics Reveals Tumor Microenvironment Heterogeneity With High-Density Progenitor Cell Regions Correlating With High-Risk Disease. [PDF]
Chien F +7 more
europepmc +1 more source
Biomass DNA: An Emerging Building Block for Advanced Materials
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley +1 more source
Vasorelaxant Effects of Wild Jujube Leaf Aqueous Extract: Endothelial NO/cGMP/SERCA Signaling, Antioxidant Activity, and AI-Based Molecular Docking. [PDF]
Alla C +11 more
europepmc +1 more source

