Results 11 to 20 of about 605,396 (385)
The effects of sepsis on endothelium and clinical implications.
Cardiovascular Research, 2020 Sepsis accounts for nearly 700,000 deaths in Europe annually is caused by an overwhelming host response to infection resulting in organ failure. The endothelium is an active contributor to sepsis and as such represents a major target for therapy.
E. Dolmatova +3 more
semanticscholar +1 more source
The vascular bone marrow niche influences outcome in chronic myeloid leukemia via the E-selectin - SCL/TAL1-CD44 axis. [PDF]
, 2020 The endosteal bone marrow niche and vascular endothelial cells provide sanctuaries for leukemic cells. In murine chronic myeloid leukemia (CML) CD44 on leukemia cells and E-selectin on bone marrow endothelium are essential mediators for the engraftment ...
Aggoune, D. +17 more
core +2 more sources
Oxidative Stress, Antioxidants and Hypertension
Antioxidants, 2023 As a major cause of morbidity and mortality globally, hypertension remains a serious threat to global public health. Despite the availability of many antihypertensive medications, several hypertensive individuals are resistant to standard treatments, and
Michael Amponsah-Offeh +3 more
doaj +1 more source
Physiology of the endothelium [PDF]
British Journal of Anaesthesia, 2004 In the past, the endothelium was considered to be inert, described as a 'layer of nucleated cellophane', with only non-reactive barrier properties, such as presentation of a non-thrombogenic surface for blood flow and guarding against pro-inflammatory insults.
Nigel R. Webster, Helen F. Galley
openaire +3 more sources
Cross-Talk of NADPH Oxidases and Inflammation in Obesity
Antioxidants, 2023 Obesity is a major risk factor for cardiovascular and metabolic diseases. Multiple experimental and clinical studies have shown increased oxidative stress and inflammation linked to obesity.
Henning Morawietz +6 more
doaj +1 more source
Frontiers in Medicine, 2022 BackgroundWe evaluated the visual outcomes and complications of “endothelium-out” and “endothelium-in” Descemet membrane endothelial keratoplasty (DMEK) graft insertion techniques.Materials and MethodsElectronic searches were conducted in CENTRAL ...
Hon Shing Ong +11 more
doaj +1 more source
Platelet kinetics in the pulmonary microcirculation in vivo assessed by intravital microscopy [PDF]
, 2002 Growing evidence supports the substantial pathophysiological impact of platelets on the development of acute lung injury. Methods for studying these cellular mechanisms in vivo are not present yet.
Eichhorn, M. E. +3 more
core +1 more source
Vascular device interaction with the endothelium [PDF]
, 2008 Copyright @ 2008 Elsevier. This is the post-print version of the article.Cerebral stents and Intra Aortic Balloon Pumps (IABP) are examples of mechanical devices that are inserted into arteries to restore flows to clinically healthy states. The stent and
Atherton, MA +4 more
core +2 more sources
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Background Vascular endothelial cell (EC) alignment in the direction of flow is an adaptive response that protects against aortic diseases, such as atherosclerosis. The Rho GTPases are known to regulate this alignment.
Angelina J. Lay +8 more
doaj +1 more source
Mercaptoethylguanidine is a selective inducible nitric oxide synthase inhibitor on pulmonary artery
Tungs’ Medical Journal, 2023 Background: Nitric oxide (NO) is a colorless and odorless toxic gas and a short-acting physiological vasodilator. NO is produced by nitric oxide synthase (NOS).
Xian-He Shyanher Wang
doaj +1 more source