Results 51 to 60 of about 25,379 (184)

Restricted TCR Diversity and Expansion of CD177+CD8+ and TLR4+CD4+T Cell Subsets in Septic Shock‐Associated Immunosuppression: A Single‐Cell Multi‐Omics Study

MedComm, Volume 7, Issue 9, September 2026.
Our study enrolled 10 septic shock patients with immunosuppression and 10 healthy controls and sorted CD8+ and CD4+ T cells for transcriptome sequencing. Disease‐specific cell types, key transcripts, and TCR features were identified using integrated analysis.
Yawen Xie, Xunyao Wu, Guoyu Zhao, Xianli Lei, Jiahui Zhang, Na Cui, Bin Du   +6 more
wiley   +1 more source

Understanding the Molecular Processes of Obesity and the Anti‐Obesity Properties of Bioactive Substances Found in Tea

Phytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
ABSTRACT Obesity, a severe worldwide health concern, is characterized as an excessive deposit of fat in the human body. It has various ramifications that endanger human health and increase the financial expense. Obesity raises the risk of several illnesses, notably cardiovascular disease, NALFD, and diabetes, and has been associated with shorter ...
Sakhawat Riaz, Fan Wenni, Danish Kamal, Umber Mubeen, Abul Hassan, Arslan Ahmed, Munir Ahmed   +6 more
wiley   +1 more source

Characterization of Phylogroups, Virulence Factors and Antimicrobial Resistance in Canine Pyometra‐associated Escherichia coli

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This study characterized 56 Escherichia coli isolates obtained from canine pyometra, which predominantly belonged to phylogroup B2 and harboured multiple virulence genes, with high multidrug resistance rates indicating potential clinical and zoonotic risks. ABSTRACT The presence of multidrug‐resistant extraintestinal pathogenic Escherichia coli (ExPEC)
İnci Başak Müştak, Murat Onur Yazlık, Beyza Nur Şitvan, Hamit Kaan Müştak, Ufuk Kaya   +4 more
wiley   +1 more source

Stapled side‐to‐side anastomosis to treat a pelvic flexure stricture in a miniature horse

Equine Veterinary Education, Volume 38, Issue 9, Page e603-e608, September 2026.
Summary Fecaliths are a recognised cause of non‐strangulating colon obstruction in horses. Although they more commonly obstruct the small colon, they can also lodge in the pelvic flexure, requiring enterotomy for removal. Stricture at the enterotomy site is an uncommon but surgically significant complication.
M. Baglioni, N. Berka, P. Matrat, L. Legrand, L. Borde‐Dore, C. de Chaisemartin   +5 more
wiley   +1 more source

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

Advanced Science, Volume 13, Issue 44, 7 August 2026.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu, Caiyan Lin, Lijie Zhang, Xue Jiang, Huawen Li, Yangzhe Wu   +5 more
wiley   +1 more source

Gut Microbiota and Ischemic Stroke: From Pre‐Stroke Dysbiosis and Acute‐Phase Changes to Therapeutic Applications

Brain and Behavior, Volume 16, Issue 8, August 2026.
Abstract Purpose Ischemic stroke poses a major global health burden, and growing evidence points to the microbiota–gut–brain axis as an important contributor to stroke pathophysiology and recovery. The purpose of this review is to summarize current knowledge on bidirectional gut‐brain communication in stroke, establishing gut dysbiosis as an upstream ...
Ruihui Weng, Gaolei Dong, Jianxin Tang, Yu Zhao   +3 more
wiley   +1 more source

The Postprandial Chronobiome in Interorgan Glucose Homeostasis

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
The postprandial chronobiome framework proposes that meal‐timed oscillations in microbial communities and metabolites may interact with host tissue clocks to shape glucose handling. The liver is the best‐supported temporal interpreter, while phase‐aware human studies are needed to establish causal interorgan effects.
Josko Bozic, Roko Santic, Marko Kumric
wiley   +1 more source

ADAMTS4 mediates LPS‐induced cardiac injury and myocardial fibrosis through proteolytic cleavage of TSP1

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
• ADAMTS4 is induced primarily in cardiac fibroblasts during sepsis. • ADAMTS4 cleaves TSP1 at the 236–246 aa functional region. • TSP1 cleavage activates TGF‐β/Smad and NF‐κB signalling in fibroblasts. • Targeting ADAMTS4 reduces fibroblast activation and cardiac fibrosis.
Zhe‐Wei Zhang, Shi‐Yan Wan, Wen Li, Xiao Lu, Rong Chen, Xin Xing, Wei Lai, Shu‐Yang Sheng, M. M. Mosebetsi, Qing‐Tao Meng, Zi‐Long Lu, Di Fan, Wan‐Li Jiang   +12 more
wiley   +1 more source

What Is Your Diagnosis? Abnormal WDF Scattergram From the Sysmex XN‐1000V in a Cat

Veterinary Clinical Pathology, EarlyView.
Javier Martínez‐Caro, Laura Chaves‐Falcón, Marta Lemos, Xavier Roura, Luis Bosch, Josep Pastor   +5 more
wiley   +1 more source

Colon‐Targeted Berberine Nanoparticles‐Embedded Yeast Microcapsules for Regulation of Gut Immunity of Sepsis

eFood, Volume 7, Issue 4, August 2026.
A schematic representation illustrating the preparation of BGNP@YM and its therapeutic effects on septic mice induced by lipopolysaccharide (LPS). (A) BBR is first encapsulated within GNPs to form BGNPs with anti‐inflammatory activity, which are subsequently coated with YM via chemical precipitation to obtain the BGNP@YM oral delivery system.
Qing‐Qing Dong, Si‐Hui Wang, Chen‐Yan Wang, Ke‐Da Yang, Xiao‐Ling Xu, Yi Shi, Wei Chen   +6 more
wiley   +1 more source