Results 121 to 130 of about 176,455 (318)
Mixing It Up With MT2: Unbiased Mass Measurements at Hadron Colliders
, 2011 Recently, much progress has been made on techniques to measure the masses of new particles with partially-invisible decays at a hadron collider. We examine for the first time the realistic application of MT2-based measurement methods to a fully hadronic ...
Curtin, David
core +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Detecting kinematic boundary surfaces in phase space: particle mass measurements in SUSY-like events
Journal of High Energy Physics, 2017 We critically examine the classic endpoint method for particle mass determination, focusing on difficult corners of parameter space, where some of the measurements are not independent, while others are adversely affected by the experimental resolution ...
Dipsikha Debnath +5 more
doaj +1 more source
Development of Reference Procedures for Broth Microdilution Antifungal Susceptibility Testing of Yeasts with Standardized Endpoint Determination [PDF]
, 1998 Koichi Makimura +4 more
openalex +1 more source
Direct Neutrino Mass Experiments
, 2016 With a mass at least six orders of magnitudes smaller than the mass of an electron -- but non-zero -- neutrinos are a clear misfit in the Standard Model of Particle Physics.
Mertens, Susanne
core +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Discriminating Electroweak-ino Parameter Ordering at the LHC and Its Impact on LFV Studies
, 2009 Current limit on the dark matter relic abundance may suggest that $|\mu|$ should be smaller than prediction in the minimal supergravity scenario (mSUGRA) for moderate $m_0$ and $m_{1/2}$. The electroweak-ino parameter $M_1, M_2$ and $|\mu|$ are then much
A. Barr +26 more
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source