Results 121 to 130 of about 2,705,124 (338)

Direct Neutrino Mass Experiments

, 2016
With a mass at least six orders of magnitudes smaller than the mass of an electron -- but non-zero -- neutrinos are a clear misfit in the Standard Model of Particle Physics.
Mertens, Susanne
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Automated approaches for band gap mapping in STEM-EELS

, 2017
Band gap variations in thin film structures, across grain boundaries, and in embedded nanoparticles are of increasing interest in the materials science community.
Granerød, Cecilie S., Prytz, Øystein, Zhan, Wei   +2 more
core   +1 more source

Determination of bacterial endotoxins in parenteral solutions produced on a small scale in a clinical hospital [PDF]

Makedonsko Farmacevtski Bilten
Two different limulus amoebocyte lysate assays of bacterial endotoxins in parenteral solutions produced on a small scale in a clinical hospital are evaluated.
Renata Bozhinovska Popovska, Tatjana Gjurichikj, Branislava Janeva, Jelena Acevska, Aneta Dimitrovska   +4 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Mass Measurement of the Decaying Bino at the LHC

, 2008
In some class of supersymmetric (SUSY) models, the neutral Wino becomes the lightest superparticle and the Bino decays into the Wino and standard-model particles.
Aad, Alwall, Asai, Asai, Bachacou, Feng, Gherghetta, Giudice, Ibe, Maltoni, Moroi, Osamu Jinnouchi, Randall, Satoshi Shirai, Shoji Asai, Sjostrand, Stelzer, T.T. Yanagida, Takeo Moroi, Toharia, Wells, Yuya Azuma   +21 more
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

The role of immunohistochemical analysis in determining the molecular subtypes of bladder cancer

Успехи молекулярной онкологии
Introduction. The results of genomic profiling of muscle-invasive bladder cancer (BC) based on messenger RNA (mRNA) extraction showed significant molecular variety of the tumors underlying the wide spectrum of clinical manifestations and responses to ...
M. V. Berkut, A. S. Artemyeva, A. V. Khokhlova, A. I. Saad, A. K. Nosov   +4 more
doaj   +1 more source