Results 81 to 90 of about 2,705,124 (338)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

DETERMINATION OF ALKALINITY AND DISSOCIATION CONSTANTS OF HIGH SALINITY WATERS: USE OF F5BC TITRATION FUNCTION

Eclética Química, 2018
Measurements of parameters expressed in terms of carbonic species such as Alkalinity and Acidity of saline waters do not analyze the influence of external parameters to the titration such as Total free and associated Carbonic Species Concentration ...
Bernadete F. Cavalcanti, Lourdes Cristina Lucena Agostinho, Luciano Nascimento   +2 more
doaj   +1 more source

Photoactivation experiment on 197Au and its implications for the dipole strength in heavy nuclei

, 2008
The 197Au(gamma,n) reaction is used as an activation standard for photodisintegration studies on astrophysically relevant nuclei. At the bremsstrahlung facility of the superconducting electron accelerator ELBE (Electron Linear accelerator of high ...
A. R. Junghans, A. Wagner, C. Nair, D. Bemmerer, E. Grosse, G. A. Bartholomew, G. Rusev, J. Klug, J. M. Eisenberg, K. D. Schilling, K. Debertin, K. Kosev, M. Erhard, R. Beyer, R. Schwengner, S. J. Skorka, Y. I. Sorokin   +16 more
core   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Measurements of |Vub| and |Vcb| from CLEO [PDF]

, 2003
I report results from the CLEO collaboration on semileptonic B decays, highlighting measurements of the Cabibbo-Kobayashi-Maskawa matrix elements |Vub| and |Vcb|.
Adam, Alexander, Barish, Bauer, Bauer, Behrens, Bigi, Bjorken, Bornheim, Briere, Cabibbo, Caprini, Chau, Chen, Cronin-Hennessy, De Fazio, Gremm, Groom, Hagiwara, Hamzaoui, Hashimoto, Hoang, Jarlskog, Karl M. Ecklund, Kobayashi, Leibovich, Leibovich, Ligeti, Luke, Manohar, Neubert, Neubert, Neubert, Rosner, Uraltsev, Voloshin, Wolfenstein   +36 more
core   +2 more sources

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

FEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman, Annika Egeler, Saskia Rödl, Johannes M. Herrmann   +3 more
wiley   +1 more source

An alternative trial-level measure for evaluating failure-time surrogate endpoints based on prediction error

Contemporary Clinical Trials Communications, 2019
To validate a failure-time surrogate for an established failure-time clinical endpoint such as overall survival, the meta-analytic approach is commonly used.
Shaima Belhechmi, Stefan Michiels, Xavier Paoletti, Federico Rotolo   +3 more
doaj   +1 more source

Cardiac magnetic resonance imaging versus computed tomography to guide transcatheter aortic valve replacement: study protocol for a randomized trial (TAVR-CMR)

Trials, 2022
Background The standard procedure for the planning of transcatheter aortic valve replacement (TAVR) is the combination of echocardiography, coronary angiography, and cardiovascular computed tomography (TAVR-CT) for the exact determination of the aortic ...
Gert Klug, Sebastian Reinstadler, Felix Troger, Magdalena Holzknecht, Martin Reindl, Christina Tiller, Ivan Lechner, Priscilla Fink, Mathias Pamminger, Christian Kremser, Hanno Ulmer, Axel Bauer, Bernhard Metzler, Agnes Mayr   +13 more
doaj   +1 more source

Heat Flux Analysis and Assessment of Drying Kinetics during Lyophilization of Fruits in a Pilot-Scale Freeze Dryer

Foods, 2023
Vacuum freeze-drying as a process for achieving high product quality has attracted increasing attention in the last decade. Particularly in the pharmaceutical field and food processing industries, lyophilization can produce high-quality products compared
Ivan Sedmak, Matic Može, Gorazd Kambič, Iztok Golobič   +3 more
doaj   +1 more source

Supersymmetry, Naturalness, and Signatures at the LHC [PDF]

, 2006
Weak scale supersymmetry is often said to be fine-tuned, especially if the matter content is minimal. This is not true if there is a large A term for the top squarks.
A. Brignole, R. Barbieri, Ryuichiro Kitano, T. Kobayashi, Yasunori Nomura   +4 more
core   +3 more sources