Results 91 to 100 of about 316,766 (308)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Protein and the Adaptive Response With Endurance Training: Wishful Thinking or a Competitive Edge?

Frontiers in Physiology, 2018
The significance of carbohydrates for endurance training has been well established, whereas the role of protein and the adaptive response with endurance training is unclear. Therefore, the aim of this perspective is to discuss the current evidence on the
Pim Knuiman, Maria T. E. Hopman, Maria T. E. Hopman, Conor Verbruggen, Marco Mensink   +4 more
doaj   +1 more source

Training in hypoxia fails to further enhance endurance performance and lactate clearance in well-trained men and impairs glucose metabolism during prolonged exercise. [PDF]

, 2010
The aim of this study was to investigate the synergistic effects of endurance training and hypoxia on endurance performance in normoxic and hypoxic conditions (approximately 3000 m above sea level) as well as on lactate and glucose metabolism during ...
Abdel-Sayed, Andreas Boss, Bailey, Bentley, Bergman, Bonen, Bonetti, Burgomaster, Chiolero, Chiolero, Christel Tran, Clark, Clark, Coggan, Coggan, Donovan, Dubouchaud, Dufour, Fabio Borrani, Faria, Frayn, Friedlander, Gardner, Hashimoto, Haufe, Hawley, Hendriksen, Hoppeler, Hoppeler, Hoppeler, Jeukendrup, Laursen, Laursen, Levine, Levine, Luc Tappy, Lundby, MacRae, MacRae, Meeuwsen, Messonnier, Messonnier, Messonnier, Messonnier, Messonnier, Miller, Morton, Philippe Schneiter, Phillips, Ponsot, R Development Core Team, Revelly, Robach, Roels, Roels, Roels, Schneiter, Schneiter, Stanley, Stepto, Terrados, Thomas, Thomas, Truijens, Vallier, Van Hall, Van Hall, Ventura, Virgile Lecoultre, Vogt, Wiesner, Wilber, Yves Schutz, Zoll   +73 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Meta‐analysis of high‐intensity interval training and alternative modalities for enhancing aerobic and anaerobic endurance in young athletes

Physiological Reports
This meta‐analysis examined whether HIIT outperforms low‐intensity endurance training (LIET), generic training (GT), or sport‐specific drills (SSD) in improving aerobic and anaerobic endurance in youth athletes.
Manuel Matzka, Mascha Lenk, Benedikt Meixner, Billy Sperlich   +3 more
doaj   +1 more source

EFFECTIVENESS OF LAND BASED ENDURANCE TRAINING VERSUS AQUATIC BASED ENDURANCE TRAINING ON IMPROVING ENDURANCE IN NORMAL INDIVIDUALS

International Journal of Physiotherapy, 2015
Background: Recently the exercises and fitness professionals have adopted water as an alternative medium for delivering programs to improve fitness and health.
Vinod Kumar .K .C , Sabitha Eunice Regima, Vikranth .G .R   +2 more
doaj   +1 more source

Effects of endurance training on the serum level of sex hormones and sperm parameters after diabetic induction by streptozotocin-nicotinamide [PDF]

, 2017
Background and aims: The aim of the present study was to investigate the effects of endurance training on the serum levels of sex hormones and sperm parameters in the induced diabetic rats by Streptozotocin-Nicotinamide.
Heidarianpour, Ali., Parastesh, Mohammad.   +1 more
core  

The impact of anabolic androgenic steroids abuse and type of training on left ventricular remodeling and function in competitive athletes [PDF]

, 2014
Background/Aim. Long-term intensive training is associated with distinctive cardiac adaptations which are known as athlete’s heart. The aim of this study was to determine whether the use of anabolic androgenic steroids (AAS) could affect ...
Babić Rade, Ilić Ivan, Nešković Aleksandar N., Putniković Biljana, Stanković Ivan, Vlahović-Stipac Alja, Đorđević Vitomir   +6 more
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Impact of protein supplementation during endurance training on changes in skeletal muscle transcriptome

BMC Genomics, 2020
Background Protein supplementation improves physiological adaptations to endurance training, but the impact on adaptive changes in the skeletal muscle transcriptome remains elusive.
Pim Knuiman, Roland Hangelbroek, Mark Boekschoten, Maria Hopman, Marco Mensink   +4 more
doaj   +1 more source