Results 71 to 80 of about 3,713,329 (299)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

EFFECTIVENESS OF LAND BASED ENDURANCE TRAINING VERSUS AQUATIC BASED ENDURANCE TRAINING ON IMPROVING ENDURANCE IN NORMAL INDIVIDUALS

International Journal of Physiotherapy, 2015
Background: Recently the exercises and fitness professionals have adopted water as an alternative medium for delivering programs to improve fitness and health.
Vinod Kumar .K .C , Sabitha Eunice Regima, Vikranth .G .R   +2 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

The effect of speed endurance training on increasing aerobic endurance of futsal extracurricular students

Purpose: This study aims to analyze the effect of speed-endurance training on increasing aerobic capacity (VO₂max) among students participating in extracurricular futsal activities.
Bird, Stephen P., Febriliana, Fanesa Amanda, Kusnanik, Nining Widyah   +2 more
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

The distance-time relationship and its use in endurance training and performance [PDF]

, 2015
The aims of this thesis were to develop a time efficient field test of the distance-time relationship, assess its validity, reliability and sensitivity and utilise the test to monitor and prescribe endurance training in distance runners. Laboratory-based
Galbraith, Andy
core  

Investigating the Effect of Endurance Training and Supplementation of Persia Rosa Extract on Mitochondrial Apoptosis of Myocardium

Journal of Ardabil University of Medical Sciences, 2020
Background & objectives: Physical training and some supplements through different mechanisms could be effective in reducing apoptosis; the aim of this study was to investigate the effect of endurance training and supplementation of Persia Rosa extract on
Aylar Imani, Marefat Siahkouhian, Pouran Karimi, Masoud Asgharpour-Arshad, Farnaz Seifi-Ski-shahr   +4 more
doaj  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Endurance training [PDF]

, 2017
Title: Endurance training Objectives: The aim of this research is to analyse the complexity of endurance growth for amateur cyclist. We will endeavour to suggest a suitable training plan for a 41 year old female. Method: All data was gained by collecting.
Borůvková, Lenka
core  

Endurance Training Of Trained Athletes-An Electromyogram Study

2005 IEEE Engineering in Medicine and Biology 27th Annual Conference, 2005
Little is known about the mechanism that improves the capabilities of athletes by high, intensity interval training (HIT). This study was conducted to determine the neurophysiological changes due to HIT. Changes in surface electromyography (SEMG) in well-trained endurance cyclists due to the training were identified.
J, Jemma, J, Hawley, D, Kumar, V, Singh, I, Cosic   +4 more
openaire   +3 more sources