Results 51 to 60 of about 104,109 (310)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Mechanisms of exercise-induced improvements in the contractile apparatus of the mammalian myocardium [PDF]

open access: yes, 2010
One of the main outcomes of aerobic endurance exercise training is the improved maximal oxygen uptake, and this is pivotal to the improved work capacity that follows the exercise training.
Kemi, O.J., Wisløff, U.
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

The distance-time relationship and its use in endurance training and performance [PDF]

open access: yes, 2015
The aims of this thesis were to develop a time efficient field test of the distance-time relationship, assess its validity, reliability and sensitivity and utilise the test to monitor and prescribe endurance training in distance runners. Laboratory-based
Galbraith, Andy
core  

Blood flow restriction endurance exercise and endurance performance in athletes

open access: yesExercise and Quality of Life
The development and advancement of sports training over time have been accompanied by continuous innovations, which significantly contribute to improving athletic performance.
Matevž Arčon, Nejc Črnčič
doaj   +1 more source

Investigation of High-Intensity Interval Training (HIIT) Studies in Tennis and Badminton Players

open access: yesSportif Bakış Spor ve Eğitim Bilimleri Dergisi, 2021
The aim of this review was to examine the studies on high-intensity interval training (HIIT) applied in tennis and badminton. Considering the duration of the tennis and badminton match, these sports are seen as an aerobic sports.
Yıldız Yaprak, Fikret Ozturk
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

DEVELOPMENT OF SPECIAL ENDURANCE OF AIKIDOISTS AT THE TRAINING STAGE OF AIKIDO TRAINING

open access: yesФизическая культура. Спорт. Туризм. Двигательная рекреация, 2021
The authors revealed the problem of insufficient intensity of performing basic aikido techniques in Aikido examinations due to the insufficient level of development of special endurance of aikidoists.
Sergey Alekseevich Yarushin   +2 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Optimizing Arm Muscle Endurance in Pencak Silat Athletes: Insights from a Literature Review

open access: yesTanjungpura Journal of Coaching Research
Background and Study Aim. Pencak Silat is a martial art that demands exceptional physical strength, agility, and endurance. Among these, arm muscle endurance plays an important role in performing effective offensive and defensive maneuvers. Improving arm
Jefrio Demitrimus Nubatonis   +9 more
doaj   +1 more source

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