Results 61 to 70 of about 104,109 (310)

Effects of Endurance Exercise Training on The Motor and Non-Motor Features of Parkinson's Disease: A Review

Journal of Parkinson’s Disease, 2015
Background: Despite the benefits of medications and surgical interventions for Parkinson's disease (PD), these treatments are not without complications and neuroprotective strategies are still lacking. Therefore, there is a need for effective alternative
Guillaume Lamotte, Miriam R. Rafferty, Janey Prodoehl, Wendy M. Kohrt, Cynthia L. Comella, Tanya Simuni, Daniel M. Corcos   +6 more
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Efeito do treinamento intervalado de saltos verticais contínuos sobre a aptidão anaeróbia e variáveis determinantes do desempenho de endurance: um ensaio randomizado [PDF]

, 2015
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Desportos, Programa de Pós-Graduação em Educação Física, Florianópolis, 2015.No intuito de desenvolver um treinamento intervalado de sprints com um novo modo de exercício, a presente ...
Dias, Jonathan Ache
core  

Endurance Training Of Trained Athletes-An Electromyogram Study

2005 IEEE Engineering in Medicine and Biology 27th Annual Conference, 2005
Little is known about the mechanism that improves the capabilities of athletes by high, intensity interval training (HIT). This study was conducted to determine the neurophysiological changes due to HIT. Changes in surface electromyography (SEMG) in well-trained endurance cyclists due to the training were identified.
J, Jemma, J, Hawley, D, Kumar, V, Singh, I, Cosic   +4 more
openaire   +3 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Protective Effect of Curcumin Supplementation and Light Resistance Exercises on Superoxide Dismutase Enzyme Activity and Malondialdehyde Levels in a Severe Endurance Training Period in Male Wistar Rats

Armaghane Danesh Bimonthly Journal, 2017
Background and aim: Extreme endurance exercises lead to oxidative stress in athletes. Therefore, the purpose of this study was to investigate the effect of curcumin supplement supplementation and light resistance training on the activity of SOD and MDA ...
A Gorzi, F Hosseini, A Azad
doaj  

Investigating the Effect of Endurance Training and Supplementation of Persia Rosa Extract on Mitochondrial Apoptosis of Myocardium

Journal of Ardabil University of Medical Sciences, 2020
Background & objectives: Physical training and some supplements through different mechanisms could be effective in reducing apoptosis; the aim of this study was to investigate the effect of endurance training and supplementation of Persia Rosa extract on
Aylar Imani, Marefat Siahkouhian, Pouran Karimi, Masoud Asgharpour-Arshad, Farnaz Seifi-Ski-shahr   +4 more
doaj  

The Effect of Endurance Training on Brain-Derived Neurotrophic Factor and Inflammatory Markers in Healthy People and Parkinson's Disease. A Narrative Review

Frontiers in Physiology, 2020
Background: One purpose of the training conducted by people is to lose bodyweight and improve their physical condition. It is well-known that endurance training provides many positive changes in the body, not only those associated with current beauty ...
Paulina Małczyńska-Sims, Małgorzata Chalimoniuk, Anna Sułek   +2 more
doaj   +1 more source