Results 71 to 80 of about 5,188,183 (302)

Gradient printing of energetic materials – First results

, 2019
In recent years, the amount of research being performed in the field of additive manufacturing of energetic materials has increased tremendously.
Heinsius1, J., Lingen, J.N.J. van, Straathof, M.H., Driel, C.A. van, Isenia, J., Rijnders, B., Otter, J.H. den   +6 more
core  

Pair distribution function analysis of ammonium nitrate - evaluation of measuring systems for energetic materials

, 2015
S.102.1-102.10Energetic materials are often nanocrystalline, amorphous, liquid or gel structured. Therefore, it is difficult to obtain structural information from these materials by conventional structure analysis using X-ray diffraction.
Herrmann, Michael, Kempa, Paul-Bernd
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Synthesis and characterization of a 1,3-dibutylimidazolium azide ([BBIm][N3]) : A promising green energetic ionic liquid

Defence Technology
In the pursuit of advancing imidazolium-based energetic ionic liquids (EILs), the current study is devoted to the synthesis and characterization of 1,3-dibutyl-imidazolium azide ([BBIm][N3]), as a novel member in this ionic liquids class.
Nawel Matmat, Amir Abdelaziz, Djalal Trache, Sabrina Achour, Ahmed Fouzi Tarchoun, Hani Boukeciat, Sourbh Thakur, Weiqiang Pang, Thomas M. Klapötke   +8 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Enhancing accuracy in equivalent in-service-time assessment for homogeneous solid propellants: A novel temperature-independent predictive model utilizing PCA of FTIR data

FirePhysChem
The present study was devoted to setting a universal T-independent predictive model of equivalent in-service-time (EIST) for homogenous solid propellant (HSP) to surpass the limits of the van't Hoff law particularly when high aging temperatures and/or ...
Salim Chelouche, Djalal Trache, Amir Abdelaziz, Ahmed Fouzi Tarchoun, Slimane Bekhouche, WeiQiang Pang   +5 more
doaj   +1 more source

Propellant charge or grain with printed energetic material layers

, 2020
Propellant charges or grains having printed layers of two or more energetic materials are described along with methods for preparing and using ...
Straathof, M.H., Driel, C.A. van
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Study on erosion prediction model of high-energy gun propellant based on machine learning

FirePhysChem
The erosion characteristics is an important reference index that affects the popularization and application of RDX-based high-energy gun propellant containing energetic plasticizer Diazidonitrazapentane (DIANP).
Maobo Yuan, Rui Wu, Jianwei Jin, Jihua Liu, Changhui He, Hongli Zhao   +5 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source