Results 61 to 70 of about 6,576,691 (245)
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Different trajectories of exosomatic energy metabolism for Brazil, Chile and Venezuela: using the MSIASM approach [PDF]
Economic development goes hand in hand with an increase in the consumption of natural resources. Some analysts use material flows to describe such relationship [Eurostat 2001, Weisz et al., 2006], or exergy [Ayres et al., 2003].
Nina Eisenmenger +2 more
core
Energy laboratory data and model directory [PDF]
Over the past several years M.I.T. faculty, staff, and students have produced a substantial body of research and analysis relating to the production, conversion, and use of energy in domestic and international markets.
Carson, J., Lahiri, S.
core
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Going beyond energy intensity to understand the energy metabolism of nations: The case of Argentina [PDF]
The link between energy consumption and economic growth has been widely studied in the economic literature. Understanding this relationship is important from both an environmental and a socio-economic point of view, as energy consumption is crucial to ...
Jesus Ramos-Martin, Marina Recalde
core
The new insight into the role of hydroxyproline in metabolism of cancer cells
Although the role of proline (Pro) in regulatory mechanisms of cell metabolism is well recognized, the interest in metabolic significance of hydroxyproline (Hyp) has received little attention.
Magda Chalecka +3 more
doaj +1 more source
A theoretical analysis of the energy metabolism associated with the conversion of glucose to fat is presented. In tissues where the pentose cycle furnishes some of the NADPH required for fatty acid synthesis, this conversion is an ATP-yielding process ...
J.P. Flatt
doaj +1 more source
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers +7 more
wiley +1 more source
An application of MSIASM to Chinese exosomatic energy metabolism [PDF]
The methodology of Multi-Scale Integrated Analysis of Societal Metabolism (MSIASM) is applied to analyze the Chinese economy. This paper presents four tasks: (i) identifying a set of benchmarks that makes it possible to compare various characteristics of
Jesús Ramos-Martín +2 more
core
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source

