Results 51 to 60 of about 6,576,691 (245)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Current state of breast meat quality in standard-yielding broiler strains

Journal of Applied Poultry Research
SUMMARY: The purpose of this study was to evaluate and compare the state of breast meat quality in the 2 most used standard-yielding broiler chicken strains on today's market: Cobb 500 and Ross 308. To achieve this, chicks from both sexes of both strains
C. Hammemi, A. Askri, M.-P. Létourneau-Montminy, N. Alnahhas   +3 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Proteomics and tracer metabolomics link GAPDH ISGylation to glycolytic control

Genome Biology
Background Ubiquitin-like protein ISG15 (interferon-stimulated gene 15) is implicated in the regulation of central carbon metabolism, but conflicting findings across experimental systems limit mechanistic insight. Here, we apply a multi-omics approach in
Denzel Eggermont, Lissa Eggermont, Nagihan Aslantaş, Fabien Thery, Katie Boucher, Antje Beling, Bart Ghesquière, Francis Impens   +7 more
doaj   +1 more source

Diurnal and postprandial changes in key metabolic markers in high- and low-yielding early-lactation Saanen dairy goats

Journal of Dairy Science
: Although diurnal variation in circulating hormones and metabolites is well-characterized in dairy cattle, limited information exists for dairy goats, despite its importance for accurate metabolic assessment in dairy species.
J.L. Kirkham, F. Zamuner, A.W.N. Cameron, E.K. Carpenter, B.J. Leury, K. DiGiacomo   +5 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Annual Energy Outlook [PDF]

, 2009
The Annual Energy Outlook 2009 (AEO2009), prepared by the Energy Information Administration (EIA), presents long-term projections of energy supply, demand, and prices through 2030, based on results from EIA’s National Energy Modeling System (NEMS).
United States. Energy Information Administration.
core   +1 more source

Metabolic Response of the Immature Right Ventricle to Acute Pressure Overloading

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundSurgical palliation or repair of complex congenital heart disease in early infancy can produce right ventricular (RV) pressure overload, often leading to acute hemodynamic decompensation.
Masaki Kajimoto, Muhammad Nuri, Nancy G. Isern, Isabelle Robillard‐Frayne, Christine Des Rosiers, Michael A. Portman   +5 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source