Results 71 to 80 of about 2,751,201 (292)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Narrowing of Charge Balance Function and Hadronization Time in Relativistic Heavy Ion Collisions [PDF]

open access: yes, 2006
The widths of charge balance function in high energy hadron-hadron and relativistic heavy ion collisions are studied using the Monte Carlo generators PYTHIA and AMPT, respectively.
Jiaxin, Du, Lianshou, Liu, Na, Li
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Dynamic Energy Balance and Obesity Prevention

open access: yesJournal of Obesity & Metabolic Syndrome, 2018
Dynamic energy balance can give clinicians important answers for why obesity is so resistant to control. When food intake is reduced for weight control, all components of energy expenditure change, including metabolic rate at rest (resting energy ...
Sunmi Yoo
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

A Practical Method for Probabilistic Analysis of Electric Power and Energy Balance of New Power System [PDF]

open access: yesDianli jianshe
[Objective] The use of deterministic methods to construct power and energy balance tables is unsuitable because of the strong randomness and frequent occurrence of extreme events caused by a high proportion of new energy grid connections. [Methods] Based
LI Wanru, GUO Jincheng, WANG Jianxue, WANG Xiuli, YANG Qian, MA Qian
doaj   +1 more source

Architectures for smart end-user services in the power grid [PDF]

open access: yes, 2010
-The increase of distributed renewable electricity generators, such as solar cells and wind turbines, requires a new energy management system. These distributed generators introduce bidirectional energy flows in the low-voltage power grid, requiring ...
De Turck, Filip   +5 more
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Energy bill and CO2 emissions of white corn (Zea mays) production systems of Calbayog, Samar, Philippines

open access: yesAdvances in Food Science, Sustainable Agriculture, and Agroindustrial Engineering, 2020
Low production in white corn is usually encountered by many farmers due to the reduction of production areas, incidence of pest and diseases, soil degradation in terms of fertility and acidity and climate change.
Archie Lauderes
doaj   +1 more source

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