Results 201 to 210 of about 796,482 (264)

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Hypothalamic prolactin receptor⁺ dopaminergic neurons regulate energy metabolism and nociceptive threshold in mice during lactation. [PDF]

Nat Commun
Chen N, Kumar S, Patel K, Li S, Wan M, Crane J, Cao X.   +6 more
europepmc   +1 more source

Blood–Brain Barrier Regulation: Evolving From Classic Strategies to Electrochemical Ion and Reactive Oxygen Species Control

Advanced Healthcare Materials, EarlyView.
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu, Caiyu Liu, Meijun Pang, Zhiyuan Shi, Dong Ming, Xiuyun Liu   +5 more
wiley   +1 more source

Combination of lonidamine with devimistat induces synergistic antitumor effects in lung cancer via multifaceted disruption of cellular energy metabolism. [PDF]

Oncol Rep
Bai X, Yang Y, Luo Y, Jing P, Hong X, Zou Y, Dai Y, Yang X, Zhou M, Xiao H, Huang Y, Guo S, Fan Q.   +12 more
europepmc   +1 more source

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

Advanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li, Ying Wu, Huimin Wei, Jinyong Teng, Zaizhi Yang, Jufang Chen, Bao Liao, Xiaoqin Huang, Lanqing Meng, Tong Li   +9 more
wiley   +1 more source

Pathogenic Mechanisms in Cervical Cancer: Energy Metabolism, Hypoxia and Therapy. [PDF]

Life (Basel)
Giorgio V, Del Dotto V, Grandi M, Grillini S, Solaini G, Baracca A.   +5 more
europepmc   +1 more source

Alpha-ketoglutarate alleviates acute pancreatitis by restoring energy metabolism. [PDF]

iScience
Li P, Shi C, Wang H, Zhan S, Zhang J, Xu D, Lv Y, Yan F, Xu S, Chen J, Wang W.   +10 more
europepmc   +1 more source

Variants in glycine decarboxylase activate catabolic mechanisms of mitochondrial energy metabolism in the brain. [PDF]

J Biol Chem
Lopez-Ramirez A, Worth AJ, Wang ZL, Yilmaz S, Hayes S, Tang HY, Farris J, Alam MS, Padmanabhan P, Haldar K.   +9 more
europepmc   +1 more source

Junctophilin-2-orchestrated calcium signalosome regulates brown adipocyte thermogenesis and energy metabolism. [PDF]

Proc Natl Acad Sci U S A
Chen B, Wang J, Qian Q, Zhang G, Wang Y, Li M, Tan R, Yang Z, Zhao W, Ciampa G, Yang Bennett DS, Liu Y, Zhu Q, Zhu Z, Masenga SK, Vue Z, Le H, Shi Q, Zingman LV, Hinton AO, Hall DD, Abel ED, Yang L, Song LS.   +23 more
europepmc   +1 more source

PARP inhibitors target cellular energy metabolism: Mechanisms of action and clinical implications. [PDF]

Transl Oncol
Li J, Mu D, Li J, Lan M, Wu W, Zhang S, Dai Y.   +6 more
europepmc   +1 more source