Results 31 to 40 of about 8,363,489 (262)

Simulated Microgravity Potentiates Hematopoietic Differentiation of Human Pluripotent Stem Cells and Supports Formation of 3D Hematopoietic Cluster

Frontiers in Cell and Developmental Biology, 2022
Microgravity has been shown to induces many changes in proliferation, differentiation and growth behavior of stem cells. Little is known about the effect of microgravity on hematopoietic differentiation of pluripotent stem cells (PSCs). In this study, we
Chiyuan Ma, Yue Xiong, Pei Han, Xueying Zhang, Yujing Cao, Baobei Wang, Huashan Zhao, Enkui Duan, Jian V. Zhang, Jian V. Zhang, Xiaohua Lei, Xiaohua Lei   +11 more
doaj   +1 more source

Microbial dysbiosis-induced obesity: role of gut microbiota in homoeostasis of energy metabolism

British Journal of Nutrition, 2020
The global obesity epidemic has necessitated the search for better intervention strategies including the exploitation of the health benefits of some gut microbiota and their metabolic products.
E. Amabebe, F. O. Robert, Tarimoboere Agbalalah, Ebiowei S F Orubu   +3 more
semanticscholar   +1 more source

Grainyhead 1 acts as a drug-inducible conserved transcriptional regulator linked to insulin signaling and lifespan

Nature Communications, 2022
Life- and healthspan of organisms can be modulated by dietary, genetic, or pharmacological interventions, which often affect metabolic pathways. Here the authors report that Grainyhead 1 is an evolutionarily conserved, drug-inducible transcription factor
Giovanna Grigolon, Elisa Araldi, Reto Erni, Jia Yee Wu, Carolin Thomas, Marco La Fortezza, Beate Laube, Doris Pöhlmann, Markus Stoffel, Kim Zarse, Erick M. Carreira, Michael Ristow, Fabian Fischer   +12 more
doaj   +1 more source

Inhibition of Col6a5 Improve Lipid Metabolism Disorder in Dihydrotestosterone-Induced Hyperandrogenic Mice

Frontiers in Cell and Developmental Biology, 2021
Hyperandrogenism is a key pathological feature of polycystic ovarian syndrome (PCOS). Excess androgen can lead to PCOS-like cell hypertrophy in the ovaries and adipose tissue of rodents.
Li-Feng Sun, Ya-Li Yang, Ya-Li Yang, Mei-Yue Wang, Mei-Yue Wang, Hua-Shan Zhao, Hua-Shan Zhao, Tian-xia Xiao, Meng-Xia Li, Bao-Bei Wang, Chen Huang, Chen Huang, Pei-Gen Ren, Pei-Gen Ren, Jian V. Zhang, Jian V. Zhang   +15 more
doaj   +1 more source

Oscillations in energy metabolism

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2010
Organisation of mitochondrial metabolism is a quintessential example of a complex dissipative system which can display dynamic instabilities. Several findings have indicated that the conditions inducing instabilities are within the physiological range and that mild perturbations could elicit oscillations.
S. Iotti, BORSARI, Marco, D. Bendahan
openaire   +4 more sources

Energy metabolism in health and diseases

Signal Transduction and Targeted Therapy
Energy metabolism is indispensable for sustaining physiological functions in living organisms and assumes a pivotal role across physiological and pathological conditions.
Hui Liu, Shuo Wang, Jianhua Wang, Xin Guo, Yujing Song, Kun Fu, Zhenjie Gao, Danfeng Liu, Wei He, Lei-Lei Yang   +9 more
semanticscholar   +1 more source

CircECE1 activates energy metabolism in osteosarcoma by stabilizing c-Myc

Molecular Cancer, 2020
Background Osteosarcoma (OS) is the most common malignant bone tumor and has a poor prognosis. The potential involvement of circular RNAs (circRNAs) in OS progression remains unexplored.
Shuying Shen, Teng Yao, Yining Xu, Deguang Zhang, S. Fan, Jianjun Ma   +5 more
semanticscholar   +1 more source

Energy metabolism

International Journal for Innovation Education and Research, 2020
Man covers energy expenditure by the oxidation of the nutrients carbohydrate, protein, fat, and sometimes alcohol. Energy expenditure is assessed with indirect calorimetry, measuring oxygen consumption and/or carbon dioxide production, and with direct calorimetry, measuring heat loss from nutrient oxidation. Energy expenditure is a function of (1) body
Luis Henrique Almeida Castro, Leandro Rachel Arguello, Nelson Thiago Andrade Ferreira, Geanlucas Mendes Monteiro, Jessica Alves Ribeiro, Juliana Vicente de Souza, Sarita Baltuilhe dos Santos, Fernanda Viana de Carvalho Moreto, Ygor Thiago Cerqueira de Paula, Vanessa De Souza Ferraz, Tayla Borges Lino, Thiago Teixeira Pereira   +11 more
openaire   +4 more sources

A naturally occurring polyacetylene isolated from carrots promotes health and delays signatures of aging

Nature Communications, 2023
To ameliorate or even prevent signatures of aging in ultimately humans, we here report the identification of a previously undescribed polyacetylene contained in the root of carrots (Daucus carota), hereafter named isofalcarintriol, which we reveal as ...
Carolin Thomas, Reto Erni, Jia Yee Wu, Fabian Fischer, Greta Lamers, Giovanna Grigolon, Sarah J. Mitchell, Kim Zarse, Erick M. Carreira, Michael Ristow   +9 more
doaj   +1 more source

Role of Inositols and Inositol Phosphates in Energy Metabolism

Molecules, 2020
Recently, inositols, especially myo-inositol and inositol hexakisphosphate, also known as phytic acid or IP6, with their biological activities received much attention for their role in multiple health beneficial effects.
Saimai Chatree, Nanthaphop Thongmaen, K. Tantivejkul, Chantacha Sitticharoon, I. Vucenik   +4 more
semanticscholar   +1 more source