Results 91 to 100 of about 478,588 (265)

The Calculation of Properties of Fracture and Experimental Certification for 00Cr17Ni14Mo2

open access: yes工程科学与技术, 2006
:The strain stress curve and the J -integral were carried out using MTS machine for 00Cr17Ni14Mo2. Energy release rates G and the J -integral were evaluated based on the virtual crack closure technique and the method for Rice's J -integral.
doaj  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Energy Release Rate of Piezoelectric Laminated Cylindrical Shell with Delamination under Circumferential Concentrated Load

open access: yesNonlinear Engineering, 2015
The delamination growth may occur in piezoelectric laminated shell with delamination under a combined electro-thermo-mechanical loading. Based on the piezoelectric theory, the variational principle of moving boundary and considering the contact ...
Jinhua Yang, Wenliang Fan
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

On the Crack Energy Density and Energy Release Rate for an Elastic-Plastic Crack

open access: yesTRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A, 1982
For an elasto-plastic crack, the crack energy density, of which the concept was proposed by author as the most important parameter to explain the behavior of crack, and the energy release rate are discussed. The results are as follows : (1) The relation between crack energy density and load-displacement curve is discussed and a method to evaluate crack
openaire   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Modeling the Flexural Behavior of Synthetic and Bio-Based Sandwich Composite Materials Under Cyclic Fatigue

open access: yesEng
This study investigates the fatigue behaviour of sandwich composite materials under three-point bending. A stiffness reduction approach was adopted to model the damage evolution as a function of fatigue cycles.
Driss Hana   +4 more
doaj   +1 more source

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