Results 101 to 110 of about 11,796,944 (252)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Energy release rate based dynamic crack propagation [PDF]
, 2014 An energy release rate based simulation method for dynamic fracture mechanics is developed to model crack initiation and propagation in elastic–plastic solid.
Lee, James, Wang, Leyu
core +1 more source
An Experimental Study of the Relation between Mode I Fracture Toughness, KIc, and Critical Energy Release Rate, GIc. [PDF]
Materials (Basel), 2023 Qiao Y, Zhang ZX, Zhang S.
europepmc +1 more source
Strain burst vulnerability criterion based on energy-release rate
, 2020 Violent rock failures such as strain burst are significant issues during excavations in rock mass under the influence of high stress and temperature. Triggering mechanism of strain burst is associated with the intrinsic rock properties, e.g.
Nguyen, G.D. +3 more
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
, 2004 The Office of Energy Efficiency and Renewable Energy (EERE) of the U.S. Department of Energy (DOE) leads the Federal Government's efforts to provide reliable, affordable, and environmentally sound energy for America, through its 11 research, development,
Laboratory, National Renewable Energy
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
The Calculation of Properties of Fracture and Experimental Certification for 00Cr17Ni14Mo2
工程科学与技术, 2006 :The strain stress curve and the J -integral were carried out using MTS machine for 00Cr17Ni14Mo2. Energy release rates G and the J -integral were evaluated based on the virtual crack closure technique and the method for Rice's J -integral.
doaj
Topics in Energy Release and Particle Acceleration in the Heliosphere [PDF]
, 2014 This thesis investigates both the release of energy in solar flares, and the acceleration and transport of particles in various astrophysical situations.
Armstrong, Craig Keith
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source